Diary of Unknown Symptoms

Mystery of the Internal Vibration

Entry for June 15, 2007

This is one amazing article on mineral ratios and I got some new facts that I didn’t know before. Apparently you should take vitamin B6 with zinc because they work far more effectively together. It also recommends that you take manganese if you are taking zinc so that the extra zinc does not overwhelm manganese causing deficiency.

Minerals
Boo Armstrong

Note: The information on this website is presented for educational purposes and
is not a substitute for the advice of and treatment by a qualified professional.

This document was provided by Continuum Magazine VOL. 4 No. 6

Immune suppression is caused by cumulative onslaughts and any diseases which result have deep-seated causes, so in order to protect yourself from disease it is essential that you address the real factors of your health. A main contributor to your underlying and deep-seated health is the levels of minerals which you have in your blood and those stored in different parts of your body.

All life, including our bodies, is made up of two fundamentally different groups of substances: organic and inorganic. Organic substances are produced by the chemical reactions of life. They are made, broken down and remade according to what we eat, breathe and soak in from our environment. They form the proteins, vitamins, carbohydrates and fats which are the basis of everything we need in order to live – muscles, nerves, skin and organs. These organic substances exist in a state of flux, participating in a series of chemical reactions out of which new substances are formed – some which we use and some which we remove as waste.

Inorganic substances are responsible for the reactions which cause this state of flux and constant rebuilding and removal of new and old cells. They cannot be created or broken down in our bodies so we only need a small amount of them and can use them again and again. These inorganic substances are minerals and they have been around far longer than any organic life forms.

We know that without them there would be no life at all because without them the reactions necessary to create life would never get around to happening. A cell that lacks proper mineral balance will fail to perform at its optimum level and the work that is cut out for individual cells is quite astonishing. As we understand more about the roles and inter-relationships between the minerals and organic life it is becoming clear that many of today’s problems, from general fatigue to the common cold or cancer may be related to mineral deficiencies or imbalances.

The human body can survive longer without all the essential vitamins than it can without the essential minerals – in fact we could not even begin to use vitamins if we had no minerals. Like the vitamins, minerals are generally consumed in minute quantities – even so the main categorization between minerals is that of major minerals and trace minerals. The major minerals have a structural role to play as well as causing reactions – for example calcium and phosphorus form a large part of the bones. The trace minerals are found in tiny quantities and just a bit too much or not enough can cause problems.

To actually get the minerals into your blood and your body you need to absorb them. Just taking a food substance into your mouth does not necessarily mean that you will derive all the potential benefits from it. You have to actually break the substance down and then get it across any barriers which are in the way, ensuring that your body does not think it is either waste or poison.

Some minerals are antagonistic towards each other, for example calcium and magnesium. They are very similar in structure and compete for spaces to jump into. This can cause problems if you have too much of one because it will prevent the absorption of the other. Many minerals are absorbed better in one chemical context than in another – for example your body may find it easier to absorb calcium from green leaves and seeds rather than milk and dairy produce. So what you eat is important both for that reason and also because it will affect the internal environment of your body, most importantly your intestines, through whose walls absorption takes place. If food passes through you quickly, as it does when you are suffering from diarrhoea, then absorption is diminished. Bacterial or fungal over-growth causes the surface area of the intestines to be reduced which results in absorption being further diminished.

You need to be able to move minerals to where you will use them once they are inside your body . We have special arrangements for transporting them around the body and for storing them in organs, like keeping iron in the liver. Both transportation and storage for minerals usually involve a protein dedicated for the task

Minerals work together in different ways – some are synergistic and help each other, while some are antagonistic. For example you should take vitamin B6 when you take zinc because they work far more effectively together, whereas zinc and manganese are antagonistic so you should take manganese if you are taking zinc supplements so that the extra zinc does not overwhelm the manganese causing deficiency. Some minerals play more significant roles in immunity than others – for example zinc is a necessary ingredient for T-cell immunity. Low levels have been associated with reduced antibody response, abnormal proportions of antibodies and defective cell-mediated immunity. You must have enough vitamin B6 to be able to use zinc properly and best food sources are pumpkin and sunflower seeds, whole grains, sea vegetables, watercress, lentils, parsley, okra and carrots. You lose lots of zinc every time you ejaculate (if you are a man) so future safer sex campaigns should involve keeping a bowl of almonds (also high in zinc) next to your bed to replace the lost zinc. Incidentally, one way of noticing zinc deficiencies is the white marks you may find in your finger nails.

Zinc is an antioxidant, as are selenium and germanium – two other trace minerals. Antioxidants are important for house keeping and getting rid of unwanted free radicals. Sodium and potassium are crucial for cell health because they are responsible (amongst other things) for water balance within your cells – too much sodium will cause flooding and all the cellular reactions will slow down. Now is a good time to get rid of the table salt and eat more vegetables and bananas which are renowned for their high potassium content. There are lots of accessible details in all libraries and bookshops about the roles of minerals and it is worth finding out some more.

Some minerals are bad for our health – these are known as heavy metals and include lead, aluminum and cadmium. The potential for receiving toxic minerals is all around us – cadmium for example is found in tobacco, oysters, some instant teas and coffees, some canned foods and the kidneys of pigs given cadmium as a worm killer, and can cause your kidneys and liver to malfunction.

Most of the minerals, especially the trace elements, are highly toxic to the body in excess. One example is iron, which is most concentrated in red meats, but also exists in more balanced proportions in dark leafy greens and sea vegetables. Iron-overload causes the sequestration of T-cells from the blood into bone marrow which makes them unavailable for cellular immunity (and lowers your T-cell count – good news for your doctor and the drug companies) – not so good for an embattled immune system. Add to this the fact that iron excess inhibits the absorption and utilization of zinc and you will begin to realize that mineral balances are fundamentally important.

Our health is largely dependent on the conditions of the soil in which our food is grown and the type and amount of fertilizers used. As we tend to focus on calories rather than the nutritional status of our plants, huge sums of agricultural money are spent on developing bigger plants which grow in less time in the smaller spaces. This drains the soil of its nutrients, so future plants which grow there will have less minerals available as will any creatures that eat them. Bearing in mind that there are not many minerals left in some soils, some types of fertilizers inhibit the uptake of certain minerals like nitrates causing crops to be deficient in magnesium. Many of our food crops are now generally deficient in magnesium, iron, zinc, selenium, manganese and copper. In order to improve our health and that of future generations we must re-mineralize our soils. In the meantime it is good to know that sea vegetables have not yet become so distorted.

Different parts of plants contain varying amounts of minerals – for example, white flour has only 6% of the magnesium that wheat germ contains, but within the agribusiness it is unprofitable to store wheat germ because it contains fat and goes off faster than white flour. It is therefore up to us, the consumers, to make informed decisions about the food we eat, and which parts of any plant, if any, we choose to call waste.

The time scale of mineral uptake and loss is long, it can be many months or even years before exposure or lack of exposure to certain elements is noted with respect to a person’s state of health and that usually takes the help of a trained nutritionist. If someone is deficient in a vitamin the problem can be treated instantaneously with vitamin supplements. With minerals, however the path to recovery is much longer.

Improving your mineral status by eating a whole food diet will ensure that you get the right minerals in the correct, purpose-built proportions and supplementing can improve the levels of some long-term imbalances with truly life-changing results. You can in fact heal yourself, if you make the necessary commitment to yourself and your lifestyle by correcting imbalances and deficiencies, introducing fewer toxins and getting rid of the ones you already have whilst increasing your life force. If you an antibody-positive diagnosis thank your lucky stars for the pause to think – if you don’t already, now is the time to start looking after yourself.

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June 16, 2007 Posted by | Health | , , , , | Leave a comment

Entry for April 10, 2007

So for a week now I’ve lowered my zinc and I’m only taking magnesium with 50 mg of B6, 50 mg of niacin and 25 mg of manganese. It’s really strange because for some reason I feel like I’m losing my magnesium and it happens after I take the lunchtime supplements.

Then I realize that it must be the manganese as I’ve had this happen before when I tried it the first time. Forget it, from here on in it’s only magnesium, B3 and B6 with vitamin C and a lower dosage of zinc.

I’ll switch to magnesium glycinate to see if that works any better.

April 17, 2007 Posted by | Health | , , , , | Leave a comment

Entry for March 03, 2007

Came across another article that talks about the relationship between copper, zinc, weak adrenals and candida. The headlines read like a summary of my health issues:

  • “Adrenal Gland Exhaustion: A Major Cause of Copper Toxicity”
  • “Excess Sugar Intake as a Cause of Copper Toxicity and Zinc Deficiency”
  • “Candida, Stress and Copper and Hypoglycemia”

This article is one of the most amazing things I have ever read.

Insight Into Copper Elimination
By Dr. Paul C. Eck and Dr. Larry Wilson

Introduction

Years of experience in dealing with copper toxic individuals reveal that such individuals experience certain difficulties while on a nutritional correction program. One common complaint is that they are unable to take their nutritional program three times a day. Some copper-toxic individuals find it difficult to take their supplements even once a day.

Stress and Increased Metabolic Rate

Any kind of stress, physical or emotional in nature, results in a necessary increase in the metabolic rate. Any increase in the metabolic rate, whatever its cause frequently results in the release of excess copper into the blood. It is to be noted that the major internal cause of a copper toxicity problem is a reduced ability to cope with stress. It is the intent of your nutritional program to increase your ability to cope with stress, hence avoiding any future excessive buildup of copper. Many of the distressing symptoms associated with copper toxicity are due to a stress-induced zinc deficiency.

Stress as a Cause of Copper Elimination

Whenever there is an increase in one’s rate of metabolism (usually due to stress, whether physical or emotional), copper is mobilized from primary storage sites in the liver and brain and is discharged into the blood. The principal way that excess copper can be eliminated from storage sites is to increase one’s rate of metabolism. People with high tissue copper levels, because of an adrenal insufficiency problem, are very susceptible to stress and consequentially suffer from periodical elimination of copper. Enabling such individuals to better cope with stress helps to prevent a buildup of excess copper in the tissues. In other words, sensitivity to stress is greatly reduced. Major copper eliminations are thus largely eliminated.

Adrenal Gland Exhaustion: A Major Cause of Copper Toxicity

Diminished adrenal activity is perhaps the single most important physiological reason for copper toxicity problems today. When adrenal activity is insufficient, ceruloplasmin (a copper-binding protein) synthesis in the liver declines. Copper that is not bound to a protein cannot be utilized, and so it is that unbound copper begins to accumulate in various tissues and organs.

According to hair analysis research conducted by Dr. Paul C. Eck, 70-80% of people tested reveal weak adrenal glands or what is termed adrenal insufficiency! Individuals with weak adrenal glands tend to store excess copper in various body tissues, principally the liver and brain. Excessive storage of copper, as we have stated previously, eventually results in organ damage.

The Importance of Zinc & Vitamin B6

Discomforting symptoms frequently occur when the individual is eliminating copper faster than their nutrient reservoirs of vitamin B6 and zinc can contain it. Many of the symptoms associated with copper toxicity relate to a copper induced vitamin B6, zinc and vitamin C deficiency. Both vitamin B6, and vitamin C are destroyed on contact with copper.3 Along with destroying vitamin B6 and vitamin C on contact, copper, in excess, causes a relative zinc deficiency. When zinc, vitamin B6 and vitamin C reserves become adequate, the distressing symptoms of copper toxicity are largely eliminated, hence the necessity to buildup the copper-toxic individual’s storage reservoirs of the above vitamins and minerals. Until the individual’s storage reservoirs of B6, vitamin C and zinc are sufficiently replete, symptoms will continue to be manifest.

Slowing Down a Copper Elimination

Numerous methods are available for slowing down the elimination of copper. Several means of slowing-down the elimination of copper would be to reduce the supplemental dosage to once a day, take or follow the recommended program every other day, add three calcium tablets three times a day and/or temporarily increase the individual’s dietary intake of dairy products. The individual must be made aware that this is only a temporary stop gap measure, because if one remained on dairy products on a continuous basis their metabolic rate would decrease resulting in an increased storage of copper. Dairy products are often effective in reducing the symptoms of a copper elimination because they temporarily reduce the individuals temporary stress-induced excessive metabolic rate.

Inasmuch as an increase in one’s metabolic rate will cause a flare-up in symptoms associated with a copper toxicity problem it becomes necessary to temporarily slow down one’s rate of metabolism. This is accomplished by increasing one’s calcium intake, increasing one’s dairy product intake, together with an increase in dietary fat intake, such as, avocadoes, nuts, salad oils, cooking oils, dairy products, etc.) Slowing down one’s rate of metabolism is definitely of value in reducing the symptoms associated with copper toxicity. When the distressing symptoms come under control, it is time to resume the original nutritional program.

Dietary Considerations: Need for Increase in Protein Intake

One of the major problems associated with a copper toxicity problem is a copper-induced protein deficiency. This no doubt occurs, in part, because an excess of tissue copper causes a zinc deficiency. “Zinc has…been found to be important in governing the net rate of synthesis of nucleic acids and protein, thereby importantly influencing tissue growth and reparative processes…”4 Adding to the problem, individuals suffering from copper toxicity frequently develop a distaste for meat protein due to their reduced ability to digest and assimilate protein. Over a period of time, a serious protein deficiency develops. As stated previously, one major reason why copper accumulates in the body is a deficiency of protein required to bind copper, thus increasing one’s metabolic rate. Although sometimes difficult, copper-toxic individuals should attempt to increase their protein intake (eggs, fish or chicken). Soy-protein products should be avoided, unless otherwise specified, if possible, inasmuch as soy products contain relatively high amounts of copper.

Copper-toxic individuals have a great need to increase their protein intake, but usually will not partake of an increased meat protein intake until their adrenal insufficiency problem is improved or corrected. Until such time, the copper-toxic individual must avail him or herself of digestive aids including hydrochloric acid and pancreatic enzymes.

An adequate level of zinc, so necessary to prevent an excessive copper buildup depends largely on the eating of red meat protein. As stated previously, individuals suffering from copper toxicity develop a strong aversion to the eating of zinc-rich red meat protein hence the tendency to the excessive accumulation of tissue copper.

Eliminate Foods High in Copper Content

Many diets today are high in copper and low in zinc content. In particular, vegetarian proteins such as soybean, nuts, seeds, tofu, avocado and grains, often highly beneficial for others, are high in copper content. Fast food hamburgers and other popular foods are also frequently soy-based. Soybean protein is coming into wider usage, due to its low cholesterol level and lower cost.

Other high-copper foods are organ meats, shellfish, wheat germ and bran, yeast, corn oil, margarine,
and mushrooms. Except for margarine, these are excellent health foods in general, but should be temporarily avoided by copper-toxic individuals.

Special Considerations Regarding Copper Detoxification

Diet for the Copper-Toxic Individual

As stated previously, copper-toxic individuals frequently have an aversion to eating protein, particularly red meat protein. It is important for such individuals to eat some protein at least twice a day, even if the quantity is small. Meat protein is rich in zinc content, a mineral essential to prevent copper toxicity and to promote the elimination of excess copper. It is for this reason (high zinc content) that red meats are often avoided. Otherwise, progress is delayed. Strict vegetarian diets are not advisable, but may be necessary for a period of time in severe cases, until adrenal activity has been adequately reestablished.

Excessive Intake of Sweets, Fruits and Fruit Juices

The majority of copper-toxic individuals have an insatiable craving for sweets, fruit, and fruit juices. Such cravings arise from the fact that copper-toxic individuals, in general, suffer from a severe potassium deficiency. Fruit, fruit juices and vegetables are high in potassium content, and hence the craving for these foods. Such foods should be limited as much as possible for optimal results. In many cases, a high complex carbohydrate diet is necessary until adrenal activity is increased.

Excess Sugar Intake as a Cause of Copper Toxicity and Zinc Deficiency

The eating of sugar and sugar-containing foods contributes greatly to a copper toxicity problem by causing a zinc deficiency. This occurs because zinc is required for sugar and carbohydrate metabolism. The greater the sugar and carbohydrate intake, the greater the chances for a zinc deficiency to develop. Individuals suffering from copper toxicity problem usually limit their diets, to a great extent, to simple carbohydrates and carbohydrates which are rapidly absorbed (vegetable and fruit juices).

A high sugar and carbohydrate diet lower tissue zinc levels. The consequences are many.

It has been established that prolonged and repeated increases in the glucose content of the blood rid the islets of Langerhans in the pancreas almost completely of zinc. Zinc is necessary for both the production and secretion of insulin, which is necessary to burn sugars and carbohydrates.

“By means of prolonged and repeated increases in the glucose content of the blood, Maske succeeded in ridding the islets almost completely of zinc.”

In other words, the eating of a sugar and a high carbohydrate diet, which is typical of the diet preferred by the copper-toxic individual, is conducive to causing a zinc deficiency. The end-result is an inability to derive sufficient energy from the metabolism of sugar and carbohydrates with a consequent buildup of copper in the tissues.

Refining of Food Removes Zinc

Processed foods should be avoided at all costs because the refining of foods, particularly cereals and grains, removes much of the zinc contained in these foods. What zinc remaining from the refining process is unavailable because the zinc is bound to phytin. Phytic acid forms an insoluble complex with zinc rendering it biounavailable.

Candida, Stress and Copper and Hypoglycemia

Eventually, over a period of time, copper is eliminated from storage sites. Future eliminations of copper, due to stress, are thus minimized. As a result, symptoms of anxiety, migraine headaches, skin disorders, severe constipation, fears, candida infections etc., are greatly minimized.

As a result of a low blood sugar induced increased adrenalin secretion, (diminished immune response) a flare-up in candida may occur.

Often a copper elimination results in the flare-up of a candida infection and the many symptoms associated with candida.

The major reason candida continues to exist in an individual is because they are unable to reduce their excessive copper storage in the liver and in the brain. Whenever they undergo stress of any kind, copper builds up in the tissues resulting in a bio-unavailability of copper. It is the bio-unavailability of copper which permits candida to thrive. In essence, sufficient copper cannot be mobilized out of liver storage because of stress and weak adrenal glands.

Candida Albicans (Yeast) Infections

Copper is a stimulant to oxidative or aerobic metabolism. Copper biounavailability, deficiency or imbalance, often results in a tendency for yeast infections. Copper compounds are used commercially to inhibit growth of yeast and fungi.

March 3, 2007 Posted by | Health | , , , , , | Leave a comment

Entry for January 05, 2007

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The day has finally arrived and the results are in. I was a little nervous about seeing him because I didn’t get his prescription filled for the higher dose of paxil. I’m hoping that I’ll ask him about the results, find a deficiency, agree to the injections and maybe he won’t even mention paxil.

His wife weighs me on the scale and I’ve dropped a few pounds. I now weigh 179 lbs and it’s the best weight I’ve been in years. I was just over 200 lbs when I started with my symptoms. My weight dropped to 180 when I had my gastro problems and couldn’t eat properly. Once I figured out it was a niacin deficiency and I could return to eating normal, my weight went back to 200 lbs. It was only when I stuck to eating healthy that I lost the weight again. I would eat oats every morning for breakfast and a couple of apples, pears and bananas throughout the day. I’ve kept up with this healthy diet ever since the acupuncture doctor made me understand the importance of a healthy diet.

He walks in looking quite happy and cheerful. He puts my file on the desktop and reads the B6 results as 397. The test came back as normal. My heart sank and I went really quiet. How the hell is that possible? Then he asked my how it was going with the higher dose of paxil.

My worse nightmare come true. The B6 test was normal and now I have to explain that I didn’t take his suggestion of paxil.

Slowly I explain that I didn’t take any paxil and he doesn’t seem bothered this time. I ask him if I can actually see the results and he hands me the paper.

“Pyridoxine normal range 20-90. My reading was above the normal range : 397.

He explained how the above normal reading was not a concern and he had done everything that I asked for. He suggested that I take a good multivitamin and that Paxil was now an option that I should consider at the advice of the neurologist. I explained that I was reluctant to try it until we had the results of the B6 level.

I left the doctor’s office with my tail between my legs. How is it possible not to have a B6 deficiency? I need to regroup. I need to document my current symptoms and continue forward. One thing I know for sure: I have a severe magnesium deficiency but I need to find out why. Maybe now is a good time to follow up with the nutritionist. Not the way I wanted to start the new year.

Doctor Google has failed.

Still vibrating…

January 5, 2007 Posted by | Health | , , | Leave a comment

Entry for January 04, 2007

Tomorrow is the big day. Here’s an article I found on the importance of B6:

DECREASE YOUR RISK OF HEART ATTACK BY 70%

By Dr. James Howenstine, MD.
September 29, 2004
NewsWithViews.com

Dr. Kilmer McCully, who discerned the importance of homocysteine in producing arteriosclerosis, believes that B6 (pyridoxine) has unique anti-oxidant properties that cause the human body to be protected from damage from sugar loaded diets by blocking the infectious problems usually caused by excess sugar. Studies have shown that individuals consuming Western diets are more depleted of B6 than other vitamins. Fats, which constitute 30 to 40 % of the calories in the Western diet, are lacking in water soluble B vitamins. Additionally, foods grown in soils fertilized for decades by NPK fertilizer (USA) are low in micronutrients including B6 even if grown organically. In addition to both these problems Vitamin B6 is fragile so much of the B6 found in western food is lost in food processing, storage, transport and cooking.

To compound this problem sugar intake depletes B6 from the body. The air we inhale, our food and medicines are full of substances that destroy B6 in our bodies and thus increase our need for it. Stress, which is high and rising, depletes the body of B6 as does the new sources of electromagnetic radiation according to Dr. Robert Becker.

Knowing the value of pyridoxine, Dr. John Marion Ellis, of Mount Pleasant, Texas gave thousands of people in East Texas 50 to 300 mg. of B6 daily. These patients made no changes in their diets, exercise, or smoking habits. Over a 10 year period Dr. Ellis’s patients had 73 % less heart attacks and anginal problems than persons living in the same region not taking B6.

January 5, 2007 Posted by | Health | , , , | Leave a comment

Entry for January 03, 2007

I didn’t take any 5-HTP supplement today and there was no chest pain. Coincidence?

I have my follow up doctor’s appointment on Friday and I’m not going to waste my time if he doesn’t have my B6 test results. Enough is enough. I shouldn’t have to wait nine weeks for a vitamin blood test. Totally unacceptable. I make a call to his office…

I leave a message for them to call me and leave a message on my home machine as I didn’t want them to call me at work.

I check for my voicemail an hour later and she returned my call. She says they received the test results yesterday. So it looks like I have a doctor’s appointment to go to on Friday.

Should be a very interesting 48 hours.

January 3, 2007 Posted by | Health | , | Leave a comment

Entry for January 02, 2007

Controversy Erupts About Safety of 5-HTP

This article first appeared in the March, 1997 issue of VRP’s Nutritional News

Disclaimer: This information may be copied and distributed freely as long as all text remains intact, unchanged and with Vitamin Research Products, Inc. listed as source. Commercial use or commercial distribution may not occur without the express written permission of Vitamin Research Products, Inc.

Controversy Erupts About Safety of 5-HTP
James South

Last month, a “WARNING ABOUT 5-HYDROXYTRYPTOPHAN” was mailed to many members of the life extension/nutritional supplementation community. This “Warning” alleges that little, if any, benefit is to be gained through use of 5 -Hydroxytryptophan (5-HTP), and that anyone using it is actually risking death!

What are the claims made against 5-HTP in this “Warning”, and what can be said about the relevance and truth of these allegations?

The “Warning” claims that 5-HTP should be used (if at all) only with a peripheral decarboxylase inhibitor (PDI). Yet large numbers of studies reviewed by Zmilacher et al (1) found 5-HTP more effective without PDI’s than with them and with fewer and less serious side effects. Zmilacher’s own study of 5-HTP both with and without a PDI reported in the same article found notably more, and more serious, side effects from 5-HTP when combined with a PDI. Thus, the relevant scientific literature simply does not support the claim that 5-HTP is neither safe nor effective without a PDI.

The “Warning” claims that without a PDI most or all of the 5-HTP will be converted to serotonin in the bloodstream outside the brain; and since serotonin does not cross the blood-brain barrier, this would nullify any hoped-for brain benefit from 5-HTP. Yet successful studies (only some of many published) using 5-HTP without a PDI (1,2,4,6,11) clearly refute this contention. Furthermore, studies infusing tryptophan or 5-HTP directly into the bloodstream of human subjects have been performed, and these studies have not found any increase in blood serotonin caused by increased blood 5-HTP. Thus, one report states: “Six healthy male subjects received … 5-hydroxy-L-tryptophan (5-HTP) … on two occasions in a randomized cross-over study. There were marked increases in urinary 5-HTP and 5-HT [serotonin] excretion after infusion of [5-HTP] … . This occurred without significant changes in blood 5-HT [serotonin] levels measured in platelet-rich plasma.” (23) Another report using intravenous tryptophan infusion stated: ” … 5-hydroxy-Trp [5-HTP] rose rapidly and massively after Trp[tryptophan] infusions, at the 5 g dose more than … 20-fold[!] … and declined rapidly to about 5-fold baseline levels within 2 hours. Whole blood serotonin levels were almost unaffected by the Trp [tryptophan] infusions [in spite of the massive conversion of the tryptophan to 5-HTP in the blood].” (24) Thus, both clinical studies and blood serotonin measurements in response to dramatically increased blood 5-HTP levels fail to support the “Warning” claims that 5-HTP without PDI will only elevate blood serotonin and not brain serotonin levels.

The “Warning” circulating in the life extension/nutrition community also states that the high blood levels of serotonin (allegedly) ensuing from using 5-HTP without PDI, would cause blood platelets to clot up, triggering a heart attack, or cause a spasm of heart arteries (coronary artery vasospasm), also triggering a heart attack. Again, if this were a real-world-problem, then the many test subjects taking 5-HTP without PDI’s should have suffered numerous heart attacksyet nowhere is this mentioned in the vast literature on 5-HTP! It should be noted here that platelet -aggregation and vasospasm heart attacks can be triggered in moments, even in perfectly healthy and non-occluded arteries. Thus, even a single dose of 5-HTP, not to mention weeks or months of 5-HTP use, would be sufficient to elicit a heart attack, if this were really a serious problem. As Byerley et al note in a major review article on 5-HTP use: “Researchers who reported on the results of various laboratory functions (hematologic [i.e., blood], liver, kidney, etc.) found that 5 -HTP caused no significant changes … . Oral administration of 5-HTP, with or without carbidopa [a PDI], is associated with few adverse side effects.” (2) As Poeldinger et al note: “In general, 5-HTP-induced adverse events worthy of note are rare within the therapeutic dosage range.” (4)

Those concerned about even the theoretical possibility of 5-HTP use triggering platelet-aggregation heart attacks or coronary artery vasospasm heart attacks may minimize any such risks through a nutrient supplement program that specifically inhibits these two problems (which, of course, can and do occur in people who never take 5-HTP). According to MelvynWerbach, M.D., 1 gm of vitamin C three times daily, 400 – 600 iu vitamin E daily, 500 -1000 mg calcium daily, 400 – 600 mg magnesium daily, 200 mcg selenium daily, and 1.5 gm EPA from fish oil daily will significantly reduce risk of platelet -aggregation and vasospasm heart attacks. (27,28)

The “Warning” also claims that Americans’ use of vitamin B-6 supplements further worsens 5-HTP’s (alleged) danger, since B-6 activates the enzyme that could convert 5-HTP to serotonin in the bloodstream. Yet experiments with monkeys (18) and rats (19) fed even “moderate excess” amounts of B-6, increased brain serotonin production up to 60%an impossible finding if B-6 would cause the bulk of ingested 5-HTP to be prematurely converted to serotonin outside the brain. And College Pharmacy of Colorado, one of America’s premier mail-order compounding pharmacies, has been selling (by prescription) a 100 mg 5-HTP with 12.5 mg B-6 (and no PDI) since 1990 with no problems.

The “Warning” also offers the scary scenario that a rare type of serotonin-secreting tumor, called “hind-gut carcinoid,” may also be associated with fibrosis of the heart muscle and heart valves, and heart failure. However, the “Warning” offers no evidence (and doesn’t really claim, but merely implies) that taking 5-HTP supplements at reasonable doses would actually cause these tumors, or the heart damage occasionally associated with them (one study found 19 out of 604 carcinoid patients with high blood serotonin and valvular heart damage). (20) Furthermore, studies of carcinoid heart patients have been done which find no correlation between blood levels of serotonin and the heart disease sometimes found with carcinoid syndrome. Thus one report notes: “We have also studied the correlation between plasma hormone levels (e.g., 5-hydroxytryptamine {5-HT} [serotonin] and substance P) and the degree of cardiac involvement… No correlation between blood levels of 5-HT or substance P and heart involvement was found.” (25) Another report states: “Analysis of the data shows that unlike animal models, there is no difference in serum serotonin and urinary 5 hydroxyindole acetic acid [the chief serotonin metabolite] levels in patients with carcinoid syndrome with or without cardiac involvement” (26) Nonetheless,prudence suggests that in those rare individuals suffering metastatic carcinoid disease, 5-HTP use should probably be undertaken only with a physician’s recommendation and supervision.

The same paragraph mentions a “tribe of South Sea islanders with right heart fibrosis as a result of eating green banana mush, which poisons them with its serotonin content.” Firstly, it should be noted that 5-HTP is not serotonin, and the brain’s rapid absorption of 5-HTP from the blood provides an “escape hatch” from the bloodstream for ingested 5-HTP, before it can be converted to serotonin in the blood. If preformed serotonin were ingested and absorbed (as from the “green banana mush”), it would not have this same “brain escape hatch” to remove it from the blood. When high serotonin diets have actually been studied, (21) increases of blood serotonin have been neither consistent, nor as high as that
seen in the carcinoid patients.

Lastly, the “Warning” asserts that taking 5-HTP is safe only if one has regular tests to determine urinary levels of 5-hydroxyindole acetic acid (5HIAA). 5HIAA is the chief breakdown metabolite of serotonin. The “Warning” asserts 5-HTP is safe only if urinary 5HIAA levels remain low. Yet the 1992 Italian obesity study11 which used 900 mg 5-HTP daily (without PDI) for 12 weeks found a 50-fold increase in urinary 5HIAA compared to the placebo-control patients. It also found no blood chemistry abnormalities in the 5-HTP group and no difference in side effects between the 5-HTP and placebo patients. The study concluded by stating: “… the good tolerance to 5-HTP treatment observed suggest[s] that this substance may be safely used in the long-term treatment of obesity.” The “Warning” claims that “Some people … could suffer from a lethal serotonin peripheral overload [from 5-HTP ingestion].” Yet in the hundreds of papers published on 5-HTP during the past 30 years, I have not been able to uncover a single reported incident of death or serious injury from oral 5-HTP use. The “Warning” also does not cite even a single published medical reference to any such presumed death or injury.

In summary, the anti-5-HTP allegations made by the “Warning” are falsified by the vast body of published scientific literature on 5-HTP. The main side effect occasionally experienced by 5-HTP users reported in the scientific literature is gastrointestinal (GI) upsetgas, nausea, diarrhea, and cramping. This GI upset happens only to a minority of users, and even then, only occasionally. It usually lessens or disappears in the first few days or weeks of use. The published studies also indicate that taking 5-HTP with food (i.e., partway through a meal or snack) also minimizes the risk of GI upset. Starting with a low dose (25-50 mg) and increasing the dose slowly (every 3 – 5 days) up to a maximum of 200 – 300 mg daily will also minimize risk of GI upset. Total daily intake should be divided into 2 – 4 doses, with no more than 100 mg per dose. Those suffering from gut disorders, such as ulcers, irritable bowel disease, Crohn’s disease, celiac disease (sprue), etc., and those with just an extremely “sensitive” GI tract, should probably use 5-HTP with great caution, or not at all. The use of aloe vera juice/gel and/or ginger extracts may lessen or eliminate the occasional GI side effects of 5-HTP.

A final note of caution: 5-HTP may intensify the effects of various antidepressant drugs. Van Praag notes that 5-HTP combined with the tricyclic antidepressant clomipramine proved more effective than clomipramine alone. (22) Yet because of the potentially powerful but unpredictable synergy to increase brain serotonin when 5-HTP is combined with serotonin-potentiating drugs, those using MAO-inhibitor drugs, tricyclic antidepressants, SSRI’s such as Prozac, Paxil or Zoloft, and the diet drugs Pondimin (DL-fenfluramine) or Redux (D-fenfluramine), should use 5-HTP only with medical supervision. Similarly, those wishing to reduce or eliminate their serotonin-potentiating drugs with 5-HTP, should do so only with medical supervision.

References

1. K. Zmilacher, et al. L-5-Hydroxytryptophan Alone and in Combination with a Peripheral Decarboxylase Inhibitor in the Treatment of Depression. Neuropsychobiology. 1988; 20: 28-35.

2. W. Byerley, et al. 5-Hydroxytryptophan: A Review of Its Antidepressant Efficacy and Adverse Effects. J Clin Psychopharmacol 1987; 7: 127-37.

3. S. Risch and C. Nemeroff. Neurochemical Alterations of Serotonergic Neu ronal Systems in Depression. J Clin Psychiatry. 1992; 53: 3-7.

4. W. Poeldinger, et al. A Functional-Dimensional Approach to Depression: Serotonin Deficiency as a Target Syndrome in a Comparison of 5 -Hydroxytryptophan and Fluvoxamine. Psychopathology. 1991; 24: 53-81.

5. H. van Praag. Management of Depression with Serotonin Precursors. Biol Psychiatry. 1981; 16: 291-310.

6. S Takahashi, et al. Effect of L-5-Hydroxytryptophan on Brain Monoamine Metabolism and Evaluation of Its Clinical Effect in Depressed Patients. Psychiat Res 1975; 12: 177-87.

7. R. Kahn and H. Westenberg. L-5-Hydroxytryptophan in the Treatment of Anxiety Disorders. J Affect Disord, 1985; 8: 197-200.

8. V. Linnoila and M. Virkkunen. Aggression, Suicidality, and Serotonin. J Clin Psychiatry. 1992; 53: 46-51.

9. L. Buydens-Branchey, et al. Age of Alcoholism Onset. II. Relationship to Susceptibility to Serotonin Precursor Availability. Arch Gen Psychiatry. 1989; 46: 231-36.

10. J. Wurtman. Carbohydrate Craving, Mood Changes and Obesity. J Clin Psychiatry. 1988; 49: 37-39.

11. C. Cangiano, et al. Eating Behavior and Adherence to Dietary Prescrip tions in Obese Adult Subjects Treated with 5-Hydroxytryptophan. Am J Clin Nutr 1992; 56: 863-7.

12. D. Murphy et al. Obssessive-Compulsive Disorder as a 5-HT Subsytem -Related Behavioural Disorder. Bri J Psychiatry. 1989; 155: 15-24.

13. C. Maurizi. The Therapeutic Potential for Tryptophan and Melatonin: Possible Roles in Depression, Sleep, Alzheimer’s Disease and Abnormal Aging. Med Hypoth. 1990; 31: 233-42.

14. G. DeBenedittis and R. Massei. 5-HT Precursors in Migraine Prophy laxis: A Double-Blind Cross-Over Study with L-5-Hydroxytryptophan versus Placebo. Clin J Pain. 1986; 3: 123-29.

15. J. Robertson and T. Monte. Natural ProzacLearning to Release Your Body’s Own Anti-Depressants. San Francisco: Harper; 1997.

16. A. Gaby. B6The Natural Healer. New Canaan: Keats: 1984.

17. H. van Praag. Studies of the Mechanism of Action of Serotonin Precur sors in Depression. Psychopharmacol Bull. 1984; 20: 599-602.

18. P. Hartvig et al. Pyridoxine Effect on Synthesis Rate of Serotonin in the Monkey Brain Measured with Positron Emission Tomography. J Neural Trans. 1995; 102: 91-7.

19. K. Dakshinamurti, et al. Influence of B Vitamins on Binding Properties of Serotonin Receptors in CNS of Rats. Klin Wochenschr. 1990; 68: 142-45.

20. M. Jacobsen, et al. Cardiac Manifestations in Mid-gut Carcinoid Disease. Eur Heart J. 1995; 16: 263-68.

21. Y. Hoshino, et al. Serum Serotonin Levels of Normal Subjects in Physi ological State and Stress Conditions. Jpn J Psychosom Med. 1979; 19: 283-93.

22. H. van Praag. Central Monoamine Metabolism in Depressions. I. Seroto nin and Related Compounds. Compreh Psychiatry. 1980; 21: 30-43.

23. T. Li Kam Wa, et al. Blood and Urine 5-Hydroxytryptamine [Serotonin] Levels after Administration of Two 5-Hydroxytryptophan Precursors in Normal Man. Bri J Clin Pharmacol. 1995; 39:327-29.

24. G. Huether, et al. The Metabolic Fate of Infused L-Tryptophan in Men: Possible Clinical Implications of the Accumulation of Circulating Tryptophan and Tryptophan Metabolites. Psychopharmacol (Germany). 1992; 109: 442-32.

25. K. Tornebrandt, et al. Heart Involvement in Metastatic Carcinoid Disease. Clin Cardiol. 1986; 9 (1).

26. R. Arora and R. Warner. Do Indole Markers Predict Carcinoid Heart Dis ease? Chest. 1986; 90: 87-9.

27. M. Werbach. Nutritional Influences on Illness, 2nd ed. “Atherosclerosis,” 57-102. Tarzana, CA: Third Line Press; 1996.

28. P. Turlapaty and B. Altura. Magnesium Deficiency Produces Spasms of Coronary Arteries: Relationship to Etiology of Sudden Death Ischemic Heart Disease. Science. 1980; 208: 198-200.

Copyright �� Vitamin Research Products, Inc.

January 2, 2007 Posted by | Health | , , , | Leave a comment

Entry for December 30, 2006

I just did a search based on the previous post suggesting that anxiety improved following the administration of pyridoxine and tryptophan. It goes on to say that a marginal B6 deficiency causing a serotonin depletion, may have produced the increased anxiety.

So here’s what I found:

Serotonin

Monoamine neurotransmitter that provides a chemical link between the neurons of the brain. Natural serotonin is produced by the body during the digestion of healthy foods that contain the amino acid L-Tryptophan.

Serotonin is one of the chemicals which regulates emotion, and it is thought to play a large role in the biology of depression, bipolar disorder, anxiety, migraine, sexuality and appetite.

People who are suffering from problems in these health areas might have a serotonin deficiency. This deficiency may be caused by poor eating habits.

As well as being found in the brain, serotonin is found in abundance in the digestive system as well as the blood stream. When the proper foods are digested, the body creates natural serotonin.

For example, whey protein milkshakes contain the amino acid L-Tryptophan. When the protein is digested, the body converts the amino acid into natural serotonin as needed. This is the way nature intended for you to get your natural serotonin, from the digestion of various healthy foods.

Ask your doctor if natural serotonin may be an alternative to drugs or a complimentary treatment. In the treatment of depression and anxiety, SSRI pills (selective serotonin reuptake inhibitors) are often taken in hopes of increasing the brain’s serotonin levels by increasing the amount of time that it stays in the brain.

However if the body has a shortage of natural serotonin, due to a poor diet, the drugs are simply trying to make the most out of the little bit of supply there is in the body.

The question is, why not also increase the supply, instead of only trying to make the little bit there is linger for a longer time? This is not to say drugs don’t have their place, consult your doctor.

But think about this. If someone has a shortage of Vitamin C and it was causing the symptoms of scurvy, would they take a drug to make the little bit of vitamin they did have last longer in their body? They might, but why not also just drink some orange juice and naturally get some more of the vitamin into the body? Hello, hello? Is health food a big mystery?

The human body is designed to produce natural serotonin from foods that contain amino acids. If someone is very low on serotonin it might be because the food they eat is junk and does not have the nutrients the body needs to support proper health.

Here is what can happen:

1. You eat a junk diet of processed and packaged foods.

2. You find yourself with a serotonin deficiency because your body can’t make any from the junk food you eat.

3. You either make the effort to eat whey protein and similar health foods that your body can use to create natural serotonin … or you don’t.

Most people don’t. Sad but true. They end up at the doctor and buy expensive pills because they wouldn’t make an effort to eat some health foods.

Here are three ways to get more natural serotonin into your body.

1. Health Foods: Drink a whey protein milkshake every day. We do. We put a scoop of chocolate flavor in a blender with a half a banana and some skim milk. It tastes delicious and helps keep your tummy flat too.

If using a blender is too much work you can get these milkshakes in ready to drink packages. Put some in the refrigerator and enjoy one a day.

2. L-Tryptophan Supplements: These were off the market for a long time due to one bad batch made by a foreign company. Now they are back and have passed the regulatory requirements for purity. One company that makes these is Doctor’s Best.

3. These super high quality brain and mood formulas are made by a company we have great respect for. The editors of this website have used many of their products with great results. Their pure fish oil is also recommended for support of brain health.

I’m trying so many things right now for candida but this does make a lot of sense. I’ve seen the supplement called 5-HTP but I never knew what it was: L-Tryptophan!

December 30, 2006 Posted by | Health | , , | Leave a comment

Entry for December 30, 2006

I’ve been telling my doctor for sometime now that I have some really low vitamin B deficiencies and luckily convinced him to give me a riboflavin injection. I noticed several improvements but he seems hung up on the anxiety diagnosis from the neurologist. Any research on B vitamins suggest that they all work together so if you have one deficiency, you’ll have several and my doctor didn’t seem interested in pursuing it any further.

Found this tonight from who else? Doctor Google:

Anxiety and the Vitamin B complex

Deficiencies of members of the vitamin B complex appear to be common in patients with agoraphobia (fear of open spaces). (1) The same is likely to be true for other anxiety-related conditions. We will review the evidence suggesting that individual members of this family may affect the experience of anxiety.

Inositol Supplementation

Inositol is a key intermediate of the phosphatidyl-inositol cycle, a second-messenger system used by several noradrenergic, serotonergic and cholinergic receptors. Since ingestion has been shown to raise inositol levels in the cerebrospinal fluid, this nutrient could potentially serve as an anti-anxiety agent.

Indeed, when a group of 21 patients with panic disorder either with or without agoraphobia received 12 grams daily of inositol or placebo in random order for 4 weeks each, the inositol supplement was associated with a significantly greater reduction in the frequency and severity of panic attacks and of agoraphobia than the placebo. Moreover, while the efficacy of the nutrient was judged to be comparable to that of imipramine, its side effects were minimal.

Niacinamide Supplementation

Niacinamide has been shown in an animal study to have benzodiazepine-like actions including anti-conflict, anti-aggressive, muscle relaxant and hypnotic effects. In contrast to niacin, it passes readily from the plasma to the cerebrospinal fluid where it is taken up into brain cells by a high-affinity accumulation system, suggesting it is the preferred form of vitamin B3 for the treatment of anxiety.

Lactate (which is associated with anxiety) reacts with niacinamide-adenine dinucleotide [NA[D.sub.+]] to form pyruvic acid and reduced NAD (NADH + [H.sup.+]). The equilibrium of this reaction favors lactate and NA[D.sup.+]), but it can be driven by adding excess NA[D.sup.+]. It may be that supplementation with niacinamide helps to drive the reaction, thus reducing lactate concentrations.

Anecdotal reports suggest that niacinamide has anxiolytic effects comparable to the benzodiazepines, and it may be particularly effective for patients whose anxiety is secondary to reactive hypoglycemia. Typical dosages are between 500 mg twice daily and 1,000 mg 3 times daily. Hoffer believes that the optimal daily dosage is just below the amount that produces nausea.

Thiamine Deficiency

Elevated lactate may also be caused by inadequate pyruvate dehydrogenase activity resulting from a thiamine deficiency or dependency. In that case, the conversion of pyruvate to acetyl CoA is inhibited, fostering its conversion to lactic acid. Symptoms of a prolonged moderate thiamine deficiency may include fearfulness progressing to agitation as well as emotional instability and psychosomatic complaints.

When more than 1,000 healthy young men were studied, those who were chronically borderline thiamine-deficient were currently feeling significantly more anxiety–although they were not customarily nervous individuals. There are no published studies on the repletion of a borderline thiamine deficiency to treat anxiety.

Vitamin B6 Deficiency

Gamma aminobutyric acid (GABA), an inhibitory neurotransmitter which is involved in the regulation of anxiety, requires vitamin B6 for its synthesis; thus a deficiency of this vitamin may theoretically result in heightened anxiety. Vitamin B6 is also required for the conversion of tryptophan to serotonin, a neurotransmitter suspected of being involved in anxiety.

When over 1,000 healthy young men were studied, those found to be chronically deficient in vitamin B6 had a significantly greater tendency to become anxious, although they were not significantly more anxious at the time of the study. Also, in an open trial, patients with hyperventilation syndrome who also had abnormal xanthurenic acid excretion (an indicator of vitamin B6 deficiency) improved following the administration of pyridoxine and tryptophan, suggesting that a marginal B6 deficiency, by causing serotonin depletion, may have produced the syndrome.

Vitamin B12 Deficiency

Anxiety may be part of the neuropsychiatric syndrome seen in advanced cases of pernicious anemia which is well-known to be caused by B12 deficiency. When cobalamin levels of more than 1,000 healthy young men were studied, those who were chronically borderline vitamin B12-deficient were significantly more anxious at the time of the study–although they were not customarily nervous individuals. Whether B12 supplementation reduces anxiety when the vitamin is borderline deficient remains to be investigated.

References

1. Abbey LC. Agoraphobia. J Orthomol Psychiatry 11:243-59, 1982

2. Benjamin J et al. Inositol treatment in psychiatry. Psychopharmacol Bull 31(1):167-75, 1995a

3. Levine J et al. Inositol treatment raises CSF inositol levels. Brain Res 627(1):168-70, 1993

4. Benjamin J et al. Double-blind, placebo-controlled, crossover trial of inositol treatment for panic disorder. Am J Psychiatry 15(7):1084-6, 1995b

So I’ve had a blood test for vitamin B12 and Thiamine and both were normal. Still waiting on the results from the vitamin B6 test. I’ve long discovered the Niacin deficiency with some great results but not for anxiety and Inositol I don’t know much about. I believe it’s included in B complex.

December 30, 2006 Posted by | Health | , , , , , , , | 1 Comment

Entry for December 28, 2006

The nutritionist from last week left me a follow up voice mail. She wanted to know if I had made a decision regarding the treatment and I’ve been thinking a lot about it lately. I think a nutritionist would be a really great thing for me but I would want a condition.

I’ll contact her on the weekend and tell her that I will start the treatment with the condition that I have the option to quit if I am not happy with the food testing analysis from the naturopath. I don’t want the same results as the last naturopath telling me that I didn’t have a magnesium deficiency from the hair analysis.

And this time I will mark the questionaires with stars to indicate the symptoms that are being hidden by my current intake of vitamins and minerals. I will also document my entire history before I meet with anyone to ensure that nothing gets missed, including my issues with the EMF exposure.

Those are my conditions.

I’ll also tell her that I am still waiting for my B6 test result from my own doctor and will persue the injection through him if I am able to.

December 29, 2006 Posted by | Health | , , , , , | Leave a comment

Entry for December 28, 2006

Recently a friend of mine was diagnosed with a kidney stone and immediately magnesium came to mind. I mentioned this to him and checked google when I got home.

KIDNEY STONES (Renal Calculi) AND THEIR RELATION TO DIET

There are five types of kidney stones:

1. Calcium phosphate stones are common and easily dissolve in urine acidified by Vitamin C.

2. Calcium oxalate stones are also common but they do not dissolve in acid urine.

3. Magnesium ammonium phosphate (struvite stones) are much less common, often appearing after an infection. They dissolve in vitamin C acidified urine.

4. Uric acid stones result from a problem metabolizing purines (the chemical base of adenine, xanthine, theobromine [in chocolate] and uric acid). They may form in a condition such as gout.

5. Cystine stones result from a hereditary inability to reabsorb cystine. Most children’s stones are this type, and these are rare.

The Role of Vitamin C in Preventing and Dissolving Kidney Stones:

The very common calcium phosphate stone can only exist in a urinary tract that is not acidic. Ascorbic acid (vitamin C’s most common form) acidifies the urine, thereby dissolving phosphate stones and preventing their formation.

Acidic urine will also dissolve magnesium ammonium phosphate stones, which would otherwise require surgical removal. These are the same struvite stones associated with urinary tract infections. Both the infection and the stone are easily cured with vitamin C in large doses. BOTH are virtually 100% preventable with daily consumption of much-greater-than-RDA amounts of ascorbic acid. Think grams, not milligrams! A gorilla gets about 4,000 mg of vitamin C a day in its natural diet. The US RDA for humans is only 60 mg. Someone is wrong, and I don’t think it’s the gorillas.

The common calcium oxalate stone can form in an acidic urine whether one takes vitamin C or not. However, if a person gets adequate quantities of B-complex vitamins and magnesium, this type of stone does not form. Any common B-complex supplement twice daily, plus about 400 milligrams of magnesium, is usually adequate.

Ascorbate (the active ion in vitamin C) does increase the body’s production of oxalate. Yet, in practice, vitamin C does not increase oxalate stone formation. Drs. Emanuel Cheraskin, Marshall Ringsdorf, Jr. and Emily Sisley explain in The Vitamin C Connection (1983) that acidic urine or slightly acidic urine reduces the UNION of calcium and oxalate, reducing the possibility of stones. “Vitamin C in the urine tends to bind calcium and decrease its free form. This means less chance of calcium’s separating out as calcium oxalate (stones).” (page 213) Also, the diuretic effect of vitamin C reduces the static conditions necessary for stone formation in general. Fast moving rivers deposit little silt.

Furthermore, you can avoid excessive oxalates by not eating (much) rhubarb, spinach, or chocolate. If a doctor thinks that a person is especially prone to forming oxalate stones, that person should read the suggestions below before abandoning the benefits of vitamin C.

Ways for ANYONE to reduce the risk of kidney stones:

1. Maximize fluid intake. Especially drink fruit and vegetable juices. Orange, grape and carrot juices are high in citrates which inhibit both a build up of uric acid and also stop calcium salts from forming. (Carper, J. “Orange Juice May Prevent Kidney Stones,” Lancaster Intelligencer-Journal, Jan 5, 1994)

2. Control urine pH: acidic urine helps prevent urinary tract infections, dissolves both phosphate and struvite stones, and will not cause oxalate stones.

3. Eat your veggies: studies have shown that dietary oxalate is generally not a significant factor in stone formation. I would go easy on rhubarb and spinach, however.

4. Most kidney stones are compounds of calcium and most Americans are calcium deficient. Instead of lowering calcium intake, reduce excess dietary phosphorous by avoiding carbonated soft drinks, especially colas. Soft drinks contain excessive quantities of phosphorous as phosphoric acid. This is the same acid that has been used by dentists to etch tooth enamel before applying sealant.

Remember that Americans get only about 500 mg of dietary calcium daily, and the RDA is 800 to 1200 mg/day. Any nutritionist, doctor or text suggesting calcium reduction is in serious error.

5. Take a magnesium supplement of AT LEAST the US RDA of 300-350 mg/day (more may be desirable in order to maintain an ideal 1:2 balance of magnesium to calcium)

6. Be certain to take a good B-complex vitamin supplement daily, which contains pyridoxine (Vitamin B-6). B-6 deficiency produces kidney stones in experimental animals. Remember:

* B-6 deficiency is very common in humans

* B-1 (thiamine) deficiency also is associated with stones (Hagler and Herman, “Oxalate Metabolism, II” American Journal of Clinical Nutrition, 26:8, 882-889, August, 1973)

7. Additionally, low calcium may itself CAUSE calcium stones (L. H. Smith, et al, “Medical Evaluation of Urolithiasis” Urological Clinics of North America 1:2, 241-260, June 1974)

8. For uric acid/purine stones (gout), STOP EATING MEAT! Nutrition tables and textbooks indicate meats as the major dietary purine source. Naturopathic treatment adds juice fasts and eating sour cherries. Increased Vitamin C consumption helps by improving the urinary excretion of uric acid. (Cheraskin, et al, 1983). Use buffered ascorbate “C”.

9. Persons with cystine stones (only 1% of all kidney stones) should follow a low methionine diet and use buffered C.

10. Kidney stones are associated with high sugar intake, so eat less (or no) added sugar (J. A. Thom, et al “The Influence of Refined Carbohydrate on Urinary Calcium Excretion,” British Journal of Urology, 50:7, 459-464, December, 1978)

11. Infections can cause conditions that favor stone formation, such as overly concentrated urine (from fever sweating, vomiting or diarrhea). Practice good preventive health care, and it will pay you back with interest.

All very interesting research. A magnesium deficiency as well as a B6 deficiency can cause kidney stones. These are both deficiencies that I believe I have but I don’t have any kidney stones. The answer? Vitamin C.

I’m not exactly sure why but I’ve always taken a vitamin C supplement. I’ve known my wife for almost ten years and she said I’ve taken it for as long as she can remember.

And that got me thinking…if vitamin C has the effect of changing the urinary excretion of uric acid wouldn’t that effect a PH test? Like the one I did on May 2nd, 2006 and determined that I had acidic urine? I was taking around 1000-2500 mg a day during that time period.

December 28, 2006 Posted by | Health | , , , | Leave a comment

Entry for December 27, 2006

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Thought it might be time to document my daily intake of vitamins, minerals and herbs for the record. I’ve been taking the core vitamin and minerals for a while now and the herbal remedies where only recently added to fight candida. The magnesium, niacin and the multivitamin are the only ones that I know if I’ve missed taking it. The multivitamin has the active form of B6 and sometimes I take it earlier in the day because I have that “weird” feeling in my head. It goes away everytime I take any form of B6.

———————————————————–

I start every morning with the candida trauma kit:

Pysillium Fibre/Caprilic Oil/Bennonite mix

Nu Life: Magnesium: 500 mg three times a day
Vitamin C: 500 mg three times a day
Niacin: 50-100 mg three times a day
Enzymes: 1 capsule three times a day

Nu Life Multivitamin: Twice a day
Olive Leaf & Black Walnut: Twice a day

Nu Life: Omega Three: Once a day (380 DHA content)
Co-enzyme Q10: Once a day
Garlic 1000 mg Once a day

Acidophilus just before bed.

I also take the Magnesia Phosphorica in between doses of magnesium if I need to. I usually get a very mild pain in my chest and it goes away the instant I take it.

For the past few months I’ve also taken a more serious approach to eating more fruits and vegetables and healthy eating. I try to eat 1-2 Fuji apples and 1-3 bananas a day. I’ll have oatmeal with flax seeds for breakfast and sometimes I’ll eat cucumbers and tomatoes as snack foods.

December 27, 2006 Posted by | Health | , , , , , , , , , , , | Leave a comment

Entry for December 26, 2006

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Went shopping to check out the Boxing Day sales. After a couple hours not finding of anything of interest, I head to the only store that wasn’t busy. The health food store! I picked up an extra strength Kyolic garlic supplement at 1000 mg, once per day. Got home and did some more googling about the effects of garlic:

Fungal Infections

Garlic in certain forms is considered a potent antibiotic and can be particularly effective against certain fungal infections. Like viruses, fungal infections are particularly difficult to treat. Traditional medical treatments for fungal infections are usually toxic and can be ineffectual over the long term. To the contrary, garlic has proven itself as an effective anti-fungal agent against candida, aspergillus and cryptococci.

A report from a Chinese medical journal delineates the use of intravenous garlic to treat a potentially fatal and rare fungal infection of the brain called cryptococcal meningitis. In the report, the Chinese compared the effectiveness of the garlic with standard medical treatment which involved a very toxic antibiotic called Amphotericin-B. The study revealed that intravenous garlic was more effective than the drug and was not toxic regardless of its dosage.

One study using liquid garlic extract found that candida colonies were substantially reduced in mice that had been treated with the garlic. This same study also revealed that garlic stimulated phagocytic activity. This implies that infections such as candida may be controlled because garlic stimulates the body’s own defenses. Applied externally, garlic oil can be used to treat ringworm, skin parasites and warts. Lesions that were caused by skin fungi in rabbits and guinea pigs were treated with external applications of garlic extract and began to heal after seven days.

Allicin is primarily a fungistatic substance which can slow or completely stop the proliferation of the microorganisms. As an external treatment, garlic has also been found to effectively treat acne and thrush.

YEAST INFECTIONS AND GARLIC

Garlic has proven over and over that it is an effective antifungal agent. For anyone suffering from recurring yeast infections, garlic should be added to the diet. Its compounds are very active against candida albicans which causes yeast infections. Some studies have shown that garlic is more potent in treating yeast infections than nystatin, gentian violet and six other reputable antifungal agents.

Yeast infections plague millions of Americans and can cause conditions such as thrush, vaginal yeast infections and intestinal yeast disorders. Candida albicans has been linked to a wide variety of symptoms including chronic fatigue, depression, infertility and allergies. Much of the scientific research done on garlic has centered around its antimicrobial activity, especially against infectious fungi like C. albicans which causes yeast infections. Chicks that were inoculated with the C. albicans organism were cured after ten days of ingesting garlic.

A study reported in Mycologia in 1977 concluded that garlic significantly inhibited all isolates of yeast-like fungi that were tested. Once again, it is important that the allicin component of garlic is present in order to receive the antifungal effect.

Some research has suggested that raw garlic was not effective against yeast infections, while aged extracts were very good. An added bonus of using garlic to treat yeast infections is that no clinical stains of C. albicans have been known to become resistant to garlic therapy.

Because high blood sugar is also related to a higher risk of yeast infections, garlic therapy has an additional advantage. Garlic compounds have demonstrated their ability to lower blood glucose levels which would help to decrease one’s risk of developing a yeast infection.

And with such strong evidence against candida, how many people have mentioned this? NONE. Not one person mentioned taking simple garlic for candida although the naturopath and the iridologist suggested a candida infection. It was never mentioned.

So I’ll try it and see what happens…

This Saturday will be nine weeks since the simple B6 vitamin blood test and not a word on the results. This is outrageous. “Our stated turnaround time is 15 days” seemed a little dated now. It has been exactly 60 days today since the blood test was taken.

60 days for a standard vitamin blood test. What a joke. It’s no wonder my doctor wants me on antidepressants…

December 27, 2006 Posted by | Health | , , , , | 1 Comment

Entry for December 08, 2006

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My follow up with the Doctor. I get weighed on the scale and my weight is 183 lbs. It’s getting better but my ideal weight should be around 170 lbs.

So the B6 test results…nowhere to be found??! He checked over his notes and he doesn’t have everything back yet.

Six weeks and no test results for a vitamin deficiency. This should really be no surprise because of my experience with the Thiamine test. The doctor said that they will follow up with the lab to find out what happened. (Why don’t they do this BEFORE the patient takes a day off work??) He mentions that there are seven other doctors with the same last name as him so usually when ever there is a delay, it’s sent to another doctor.

How reassuring…

He asks me about paxil. I told him that I had started taking it and it had no effect on the vibration. So what does he do? (I’m half expecting him to say let’s wait for the B6 test results.) Nope… instead it my worst fear. He has decided to increase the dosage and write the prescription.

He can write the prescription but this time I’m not going through with it. I’m not doing anything else until I get my B6 test results in my hand.

December 8, 2006 Posted by | Health | , , | Leave a comment

Entry for December 07, 2006

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Today I decided to tackle this candida on my own terms. So I started the Yeast Buster Kit from the local health food store.

I have a follow up with my doctor tomorrow and I’m really hoping he has my B6 test results. I’ve been taking paxil now for two weeks and guess what? No effect on my vibration whatsoever. I wish to god he’d deal with the root cause. I think deep down he’s pissed because I could be right.

December 8, 2006 Posted by | Health | , , , , | Leave a comment

Entry for October 28, 2006

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Unfortunately I had to wait a week before I could get to a lab for my blood test. At least now it’s done and we’ll find out for sure if it’s my level of B6.

My doctor did the riboflavin injections so easily I wish he would stop messing around and give me a B6 injection. I’ve been taking B complex now for over a year and there are clear risks about taking 500 mg of B6 for long periods of time.

November 1, 2006 Posted by | Health | , | Leave a comment

Entry for October 22, 2006

I had a really interesting experience today. I was running out of my supply of vitamin B6 so I head to the local health food store. As I was looking at the vitamins, the lady asked me if I needed any help. Usually I tell them that I’m okay and brush them aside. Today I decided to ask her about the absorption of B6. She questioned why I thought I had a B6 deficiency because she said it’s unusual for men and more common among women. I asked her about B complex in the liquid form and she agreed that it had a better absorption rate so I decided to purchase some to give it a try.

She said from looking at my appearance she suspected I had a mineral deficiency rather than vitamins and commented on my pale skin and dark circles under my eyes. I somehow mentioned about my problem with magnesium and she started telling me about how vitamin deficiencies can be caused by exposure to electromagnetic fields.

WOW! I couldn’t believe my ears. I almost never mention my stories with EMF exposure for fear that people would really think I was a raving lunatic. But not this time… it was mentioned to me so I opened up and explained some of my discoveries and she appeared quite interested. I continued by telling her the success I’ve had using Google for my symptoms instead of the doctors and she said I should see a real doctor and stop using the internet and recommended an in-store homeopathic doctor.

As I was standing there talking to her, a customer came in and purchased a bar of soap. The lady behind the counter seemed to know her quite well and mentioned my B6 deficiency to her. She asked me if would mind trying a test and I agreed. She asked me to hold my arm out and push against it when she pushes on it.

She asked me how old I was and being that my birthday was in two days, I answered 36 just as she pushed on my arm. She told me that my age was incorrect. I gave her my correct age and my arm didn’t go down as far. Okay so I’ve seen this before with the Iridologist…it’s applied kinesiology.

She gave me a bottle from the shelf and asked me to hold it across my chest. She pressed on my arm and it fell down low and she commented on that I didn’t need it. We did the same thing with my liquid B complex and my arm stayed up high when she pushed on it.

Interesting but was it realistic? Who doesn’t need B complex?

November 1, 2006 Posted by | Health | , , , , , , | Leave a comment

Entry for October 21, 2006

My doctor thinks I have anxiety. I would disagree however, I would say that my body is in a state of anxiety. I know I have these upward lines in my pupils and the iridologist was the first to mention anxiety and explain it. But nobody has mentioned that it can be caused by a B vitamin deficiency… Dr Google?

A deficiency of vitamin B6 (pyridoxine) causes extreme anxiety, nervousness, confusion, and melancholy. Vitamin B6 is easily destroyed by heavy use of alcohol, drugs and refined sugars.

A quick google search and I have the answer that I’m looking for. These doctors are so caught up in their world of drugs. If this B6 blood test comes back as extremely low then all of my problems are related a vitamin deficiency that nobody could figure out except me and doctor Google.

How embarrassing… Modern medicine is antiquated.

I’d love to order the injectable B6 vitamin from Romania and have it with me when he has the results of my blood test. I’ve been wrong before but my problem is I keep looking for the one thing that is causing my symptoms and that is my biggest problem: my symptoms are caused my a number of different deficiencies. Niacin, riboflavin, magnesium and now possibly pyridoxine?

My theory goes like this: My magnesium and B6 have been low for years and I believe that the combination low levels of B6 and magnesium caused the vibration/anxiety. Losing the B6 caused me to lose niacin and later riboflavin. Then I started taking B vitamins which helped but I was ignoring the magnesium.

Some more information:

Functions: Pyridoxine and its coenzyme form, pyridoxal-5-phosphate, have a wide variety of metabolic functions in the body, especially in amino acid metabolism and in the central nervous system, where it supports production of gamma-aminobutyric acid (GABA). Many reactions, including the conversion of tryptophan to niacinand arachidonic acid to prostaglandin E2 require vitamin B6. The pyridoxal group is important in the utilization of all food sources for energy and in facilitating the release of glycogen (stored energy) from the liver and muscles. It helps as well in antibody and red blood cell production (hemoglobin synthesis) and in the synthesis and functioning of both DNA and RNA. By helping maintain the balance of sodium and potassium in the body, vitamin B6 aids fluid balance regulation and the electrical functioning of the nerves, heart, and musculoskeletal system; B6 is needed to help maintain a normal intracellular magnesium level,which is also important for these functions. The neurotransmitters norepinephrine and acetylcholine and the allergy regulator histamine are all very important body chemicals that depend on pyridoxal-5-phosphate in their metabolism. Also, the brain needs it to convert tryptophan to serotonin, another important antidepressant neurotransmitter.

Pyridoxine is especially important in regard to protein metabolism. Many amino acid reactions depend on vitamin B6 to help in the transport of amino acids across the intestinal mucosa into the blood and from the blood into cells. By itself and with other enzymes, pyridoxal-5-phosphate helps build amino acids, break them down, and change one to another and is especially related to the production and metabolism of choline, methionine, serine, cysteine, tryptophan, and niacin.

The body has a high requirement for vitamin B6 during pregnancy. It is important for maintaining hormonal and fluid balance of the mother and for the developing nervous system of the baby. Pyridoxine may somehow be related to the development and health of the myelin covering of the nerves, which allows them to conduct impulses properly.

This is making so much sense that I feel really stupid for missing it. I shouldn’t really feel bad. It’s the doctors that are paid to figure it out, not the patient.

October 21, 2006 Posted by | Health | , , | Leave a comment

Entry for October 20, 2006 *D*

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All last night I was planning on what I would say to the doctor and I have a plan.

First thing he ask me about was if I had any tingling. Nope, not since the first riboflavin injection. Secondly he asked me about taking St. John’s Wort. Nope, did nothing for me.

I started telling him about how I did some experiments and I’d like to go in a new direction. He seemed very interested so I told him how I found a magnesium supplement that seems to be working better than any of the others and he was happy to hear about that. Then I told him about how I stopped taking the B vitamins and I’d get a weird feeling in my head. So I continued only with B6 and the weird feeling never came back. His face was more interested and he said if I suspected a B6 deficiency, then we can test for it. GREAT NEWS!

Then he told me how he would like to follow the recommendation from the neurologist. Huh? This caught me off guard because he never mentioned anything about him until now. He said he’d like to give me something called “Paxil CR” in a very small dosage to start. He mentions that it is used for depression and general anxiety disorders and continues about the side effects and that if I didn’t like it, I could stop taking it. He said it may not have any effect and on a scale of 0-10 it may only have an effect of a 2. Hardly seems worth taking but I agreed to continue with his approach if he took mine.

He wrote out a blood test for pyridoxine and added B12 and folic acid. Since it was a blood test, I asked him to check my level of triglycerides and he agreed but he said it would now need to be a fasting blood test.

I go down to the pharmacy and they fill out my prescription. As the pharmacist hands it to me she says how it may cause drowsiness and dizziness and says it could be three weeks until I feel any benefits.

Not so sure I like the sounds of the side effects so I call my wife and explain what happened. She looks it up on the internet and reads me a few more of the side effects including suicidal and mentions that there is a listing for it on crazymeds.com! She is adamant that she doesn’t want me taking this medication and I agree. We’re both confused as to why the doctor felt it was neccesary to take paxil when I clearly don’t have the symptoms to justify taking it.

The only symptoms I still have are an internal vibration and weak muscles. All of my other symptoms have disappeared though my own methods of vitamins and mineral supplements.

October 21, 2006 Posted by | Health | , , , , , , , , , , | Leave a comment

Entry for October 17, 2006

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Four capsules of the new magnesium is still not enough. I raise it again to six capsules. Two at each meal for a total of 1500 mg. I have my follow up doctor’s appointment on Friday and I’m not sure what to tell him other than the St. John’s Wort has done absolutely nothing. I’m still eating 2-4 bananas a day and I don’t feel any improvement. I’ve noticed that if I miss taking the B complex, I get this weird feeling in my head. Almost like the tingling with the riboflavin but it’s more mild. I still suspect a B6 deficiency so I’ll stop taking my B complex vitamins and try taking B6 by itself for a while but this time I’ll try something different. I have B6 in a 250 mg dose and usually I take it twice a day. This time, I’ll split the pills and take four throughout the day at 125 mg.

There’s been a lot of talk in the news lately about the cost of eating healthy. Drinking carrot juice will give you botulism, eating spinach will give you e-coli…chemical residue in our fruits and vegetables… It never seems to end. And now we have the new breakfast sandwich at Tim Hortons.

Tim Hortons Breakfast Sandwich

Innocent-looking sandwich packs a wallop of fat and sodium.

Nutritional breakdown:

Sausage, Egg and Cheese: 500 calories, 34 g fat (20 g saturated, 0.5 g trans), 32 carbohydrate (1 g fibre), 18 g protein, 920 mg sodium

Bacon, Egg and Cheese: 400 calories, 24 g fat (17 g saturated, 0.5 g trans), 31 g carbohydrate (1 g fibre), 16 g protein, 740 mg sodium

Analysis: Tim Hortons is now offering some protein at breakfast time this is good news. The bad news is that the protein comes with a lot of saturated fat (a day’s supply) and sodium (one-third of a day’s supply).

Health Canada recommends a total of 20 g per day of saturated and trans fats. Well, if you pull up to the drive-in and order your Sausage, Egg and Cheese Breakfast Sandwich, you should just turn around and go home, because you will have had your entire day’s intake of saturated and trans fats. The daily value (DV) for sodium is 2,400 mg, which is about the amount of sodium in 1 tsp of salt. The breakfast sandwiches have 740-920 mg of sodium.

When I asked Tim Horton’s about this, company spokesperson Diane Slopek-Weber stated that their customer research overwhelmingly told them that the most popular choice for a hot breakfast sandwich, was one that included egg and meat. Given their wide menu selection and ordering options, their customers can choose for themselves.

Alternative: The Breakfast Sandwich is made to order, so you can ask for a multigrain bagel instead of the tea biscuit, with only egg and/or cheese. This will change the nutrition breakdown to 380 calories, 10 g fat (so you can keep driving to work).

How does it compare to McDonald\’s? The Sausage McMuffin with Egg has 440 calories, 26 g fat (10 g saturated, 0.4 g trans), 29 g carbohydrate (2 g fibre), 20 g protein, and 930 mg sodium. The Bacon & Egg McMuffin has 310 calories, 14 g fat (5 g saturated, 0.3 g trans), 29 g carbohydrate (2 g fibre), 16 g protein and 710 g sodium.

This becomes a lesson in relativity. Tim Hortons has created something so bad, it makes McDonalds look good. Perhaps this should be their new marketing position.

Take it or leave it: Keep driving.

October 21, 2006 Posted by | Health | , , , , , , , | Leave a comment

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