Diary of Unknown Symptoms

Mystery of the Internal Vibration

Entry for January 31, 2008

So now I discover a link between SAM-e and melatonin.

SAM-e Is Necessary for Melatonin

One of the most exciting things about SAMe is that it is melatonin’s daytime equivalent. The natural synthesis of melatonin during the night is dependent on the synthesis of SAMe during the day. SAMe is necessary for the biochemical reaction that converts serotonin into melatonin. (Serotonin is the neurotransmitter that drugs like Prozac elevate). SAMe and melatonin are entwined in a circadian rhythm that see-saws back and forth as the sun rises and sets. SAMe is melatonin’s other half: when melatonin levels shoot up at night, SAMe stays low. But during the day, when melatonin falls, SAMe levels climb. Without adequate SAMe during the day, neither melatonin nor serotonin can be synthesized. And both are dependent on light and dark.

One of the most fascinating animal studies on SAMe and melatonin was published in the Journal of Neurochemistry in 1995. Researchers demonstrated in great detail the perfect orchestration that occurs between levels of SAMe and melatonin. The so-called “nyctohemeral” rhythm (pertaining to both day and night) was documented almost minute-by-minute. Data were translated onto graphs showing the see-saw relationship between melatonin and SAMe (Fig. 1).

Both melatonin and SAMe are controlled by an internal “clock” that knows lightness from darkness. In the evening, about 30 minutes before sunset, levels of SAMe shoot up to their highest level. They stay there for about an hour, and then suddenly drop. When this happens, melatonin kicks in. Melatonin increases for four hours, while SAMe drops. Five hours into the night, melatonin hits its high, and SAMe hits its low. Melatonin stays elevated until three hours before sunrise, when it abruptly falls. Meanwhile, SAMe builds up. Five hours into the day (around 11:00 A.M.), SAMe reaches its peak level again, then begins a gradual descent until evening.

Serotonin levels follow roughly the same pattern-higher during the day and lower at night. It appears that the serotonin synthesized during the day is used at night to make melatonin. SAMe is absolutely crucial for the natural synthesis of melatonin because it donates a methyl group molecule to the enzyme that converts the acetylated form of serotonin to melatonin.

Melatonin is not traditionally though of as a hormone that effects mood, but it does. When melatonin levels are low, you tend to wake in the wee hours in a panicked state, even if things may be generally okay in your life. You will wake fearing the worst about the least important things or feeling depressed for no real reason. Melatonin is made from the amino acid tryptophan, which also makes serotonin. It’s production in the brain requires methionine and SAMe.

What a fantastic article. Off to the health food store looking for SAM-e!

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August 17, 2009 Posted by | Health | , , , | Leave a comment

Entry for October 21, 2007

Time to change up the vitamins a little. Today I’m going to add potassium. People with stressed adrenals are supposed to be low in potassium and it’s something I’ve added here and there but to change things up, I’ll add it again. I’ve also read about people with high sugar diets who can have low levels of potassium. It’s worth trying it again. I’m always thinking that I’m missing something obvious or overlooked something simple but until I get it, I will keep trying…

Also been doing a lot of reading about something called Glutathione and how a supplement called “NAC” can help.

7 Natural Ways To Increase Glutathione Production

Glutathione has recently become a cornerstone to improving health naturally.

You may already be aware that increasing the amount of glutathione your body produces each day is very beneficial to many of the natural systems that make and keep you HEALTHY.

Hopefully, you are also keenly aware that your personal level of glutathione directly affects your body’s ability to reduce and control chronic inflammation.

So, how does one increase personal glutathione production?

7 Natural Glutathione Boosters

L-Cysteine
Since the amount of cysteine in our body determines how much glutathione your body can make, why not just eat cysteine as a supplement? Well, you can, but research shows there would be negligible benefits and potential risks. Cysteine taken as a dietary supplement can promote hypercysteinemia and potential toxicity.

L-Methionine
Methionine is indeed a precursor of glutathione but the metabolic transformation of methionine into glutathione is a complex process which has the potential for “going astray”. For example, methionine is also a precursor of homocysteine, a risk factor in the development of atherosclerosis (hardening of the arteries).

Melatonin
Melatonin is produced by the pineal gland in the brain and has many roles in the body, one being its ability to raise glutathione levels in certain tissues of the body, including brain, liver, and muscle tissue. The long term safety of products that promote melatonin production has not been established and should be used in consultation with appropriate health professionals.

Glutamine
Glutamine is an amino acid found in abundance in our body. It is tremendously beneficial to the body and is easily found in a healthy diet. Also, supplemental glutamine must be kept absolutely dry or it will degrade into ammonia, a toxin to the body. Due to its abundance in a healthy diet and the risks of storing it, glutamine is not an ideal supplement.

Lipoic Acid (alpha-lipoic acid)
Lipoic acid occurs naturally in the body but can also be taken as a supplement with effectiveness. This supplement works well in conjunction with healthy levels of glutathione but studies show that if taken by a person whose glutathione levels are too low, lipoic acid actually promotes oxidation.

Silymarin (milk thistle)
This herbal extract seems to stimulate the growth and regeneration of damaged liver cells but also has been shown to significantly increase glutathione production. However, some toxic reactions are noted by some, such as gas, cramps and diarrhea.

Whey Proteins
Fresh or “bioactive” milk whey contains potent glutathione precursors. Unfortunately, by the time milk reaches your table, it has been pasteurized and has lost its bioactivity, and its glutathione enhancing benefits. However, a neutraceutical called Immunocal is available which is essentially the whey proteins harvested from milk and kept in a bioactive or undenatured state. There are no known side effects associated with taking bioactive whey proteins and, since there is no lactose in whey proteins, lactose intolerant people are not adversely affected.

Here’s another suggestion I found:

Raise glutathione levels:

  • Selenium 200 mcg/day
  • N-acetyl-cysteine 1-2000 mg/day (especially if prone to nasal congestion)
  • l-glutamine: 3,000 mg/day (especially if prone to stomach irritation)

January 17, 2008 Posted by | Health | , , , , , , , , , | Leave a comment

Entry for February 24, 2007

Brain Chemicals and Modern Life

It all comes down to our chemistry. Fidgeting, concentration, sleep, energy levels, mood swings, even the ability to sweat are controlled by the chemicals lurking about our bodies. Serotonin, dopamine, norepinephrine, melatonin, insulin, and prostaglandins are some of the more important ones…and these in turn are influenced strongly by stress, diet, exercise, sunlight, sleep and other life style factors. Of course the life style of today is radically different than it was 20,000 years ago. Consider how these factors from modern life commonly influence us:

  • Being indoors (lack of sunlight): Reduced melatonin
  • Stress: Reduced serotonin
  • Modern food processing: Fatty acid imbalances and chemical sensitivities
  • High sugar/carbohydrate and low-fat diet: More insulin; prostaglandin imbalance
  • Lack of exercise: Decreased serotonin and dopamine
  • Lack of sleep: Reduced serotonin
  • Poor nutrition: Reduced serotonin
  • Boring classes/job, lack of activity: Reduced dopamine & norepinephrine.
  • Deionized air: Reduced serotonin

Reduced serotonin levels from stress, lack of sleep & exercise, poor nutrition, and lack of sunlight are connected with ADD, irritability, depression, aggression, anxiety, lack of concentration, chronic pain, restlessness or fatigue, nausea, obsessive-compulsive disorder, weight gain or loss, fibromyalgia, arthritis, chronic fatigue syndrome, heat intolerance and other syndromes. Fluctuating serotonin levels are connected with bipolar disorder (manic depression) and hypomania. You don’t have to feel depressed or anxious; symptoms may be purely physical.

Reduced dopamine/norepinephrine caused by boring surroundings and lack of exercise may manifest as ADD, impulsivity, lack of concentration, restlessness, and depression or loss of pleasure. Dopamine is the “feel good” chemical which illegal drugs mimic (such as cocaine, heroin, marijuana) as well as cigarettes, coffee and alcohol. Ritalin and other ADD drugs are thought to increase dopamine activity.

Modern food processing has completely altered the types of fatty acids we consume. Since our brain is composed largely of fatty acids, we are missing the “bricks” needed for normal brain development and repair. In addition, we are eating lots of man-made chemicals. Food colors, for example, are mostly made from petroleum.

Reduced melatonin from lack of sunlight may disturb the sleep cycle and cause seasonal depression (called SAD).

Lots of sugars and carbohydrates lead to increased insulin levels. High insulin tells the body to store what you just ate as fat, thereby dropping your blood sugar concentration. Your brain can burn only sugar, so it is deprived of food. Poor concentration and depression can result. Hypoglycemia (low blood sugar) can lead to diabetes. Also, the low blood sugar make you hungry, which causes you to eat more sugar or carbohydrates, and the cycle is repeated. Finally, insulin levels affect serotonin levels and many systems throughout the body.

Poor nutrition can result in lower levels of chemicals like serotonin. Vitamins B6, C and E (the stress vitamins) are especially important.

February 25, 2007 Posted by | Health | , , , , , | Leave a comment

Entry for June 15, 2006

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Woke up this morning with the vibration again. Didn’t see any effect from the second dose of Melatonin….

With all of this research on Iridology, I also come across the Sclerology which is the study of the white area of a person’s eye. I find this very interesting as my daughter is seven months old and the whites of her eyes are so pure it’s unbelievable. Mine on the other hand… I have a distinct red vein coming from the inside corner of eye upward on a fourty-five degree angle to my iris and I have this in both eyes. What does it mean? No idea!

Sclerology

Sclerology is the science and art of observing the markings and colorings in the whites of the eyes as signs of compromised health. These markings constitute images of pathological conditions and imbalance which starts to manifest in the body.

The Value of Sclerology

The Sclera analysis adds valuable information to the Iris analysis. The iris information shows inherited strengths and weaknesses, genetic traits, time risks, traumas, space risks, emotional traits while the Sclera analysis verifies and enhances data obtained by physical iridology and other health evaluation techniques. Sclerology shows the current health situation physically and emotionally. The client then can be educated on potential conditions before they manifest as symptoms, understand both inherited and developed health predispositions, and reveal pathology that is past, current and potential. Sclerology enhances clinical health evaluation practice significantly.

What can be seen in the Sclera?

  • Stress and congestion of any significance in every area of the body
  • In which organs or tissues pathology begins
  • The spread of disease from one organ to another, which organs are involved, and to what degree (cause and effect)
  • Physical injury, various types of trauma, metabolic diseases and tumor development
  • Infection by various categories of parasites and other harmful organisms
  • Disease syndromes, and how they develop
  • Emotional sensitivity and reactive-emotion-related disease
  • Cardiovascular, liver, and all other organ disorders
  • Risk for a heart attack or stroke
  • Lymphatic-Immune response and its composite
  • Drug-induced disorders
  • Tumor and neoplasm development
  • Sugar metabolism disorders
  • Effect of X-Ray, microwaves on body tissues
  • The efficiency of a given therapy through time, healing signs

The History of Sclerology

Drawings from Chinese texts suggest that they knew and practiced Sclerology since ancient times. It is likely that other cultures have a similar tradition, like the Native American Indians. However, in those most ancient cultures, knowledge was passed orally. Dr. Stuart Wheelwright (ND) was introduced to the Nez Perce and Blackfoot Indians who taught him their use of sclerology. He made drawings based on that information and produced the first western map in 1968. The second map is from the early 1970`s and was done by Dr. Dory Dretton from his studies with Dr. Clarence Patrick “Sundance” Hathaway (the Blackfoot Native American) and Dr. Wheelwright. Modern maps were developed by Dr. Jack Tips and by Leonard Mehlmauer ND based on their most updated research in the field of sclerology.

June 15, 2006 Posted by | Health | , , | Leave a comment

Entry for June 14, 2006

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Woke up this morning with the vibration again. Didn’t notice any effect from using the Melatonin….

At the request of a friend, I take my EMF meter to work. He wanted to know the safe range of the microwave radiation. We’re in the lunchroom and we figure out the safe distance with the microwave on. Then we discover that there is still EMF from the microwave even when it’s turned off. HOLY COW! We check the other microwave and it’s the same.

We decide to check our cell phones with the meter. For my phone there is no EMF while it is on and when it rings, it peaks at the safe level of 2. We try my friends phone and it reads very high when the phone rings. As we are doing this, another friend wants to test his cell phone and it measures very high and it’s not even ringing!

Later I ask him if I could get a picture for the blog and he agrees. He comes over to my desk and he places the phone down and I put the meter beside it to get a photo. The meter reads nothing whatsoever. I check the meter and it’s turned on but there is no reading.

He puts it back into the leather case and I try it again in disbelief. This time it reads off the chart. Huh? He takes it out of the case and there is no reading. I put the meter next to the case and it reads high again. It’s reading high on the magnet clip that keeps the phone inside the pouch.

This is very weird…electromagnetic radiation from a magnet? Is this what they call healthy magnetic therapy? Or is this the bad kind of EMF? I have to do some more research when I have time…

June 14, 2006 Posted by | Health | , , , , | Leave a comment

Entry for June 13, 2006

Still bothered by what happened yesterday with the hydro lines, I look up the effects of electromagnetic frequencies on the brain. I come across an article that suggests that EMF exposure reduces the hormone Melatonin. Dr. Google?…

Electromagnetic radiation – A threat to our health

Electromagnetic radiation is the big issue he is involved in at the moment—radio waves from radio and TV towers, microwaves from cell phones, cell sites, mobile phones, cordless phones, and microwave ovens (the last being a minor problem compared with the others). The background radiation has been rising significantly by factors of thousands in the general population since the Second World War. Cancer is partly genetic, but largely environmental. Our food, the toxins in the environment like air pollutants, benzene, toxins in food like saccharine, are shown to be potential carcinogens, all those PCVs and other fairly toxic chemicals, can damage cells, but evidence is very strong that electromagnetic radiation damages cells in a way that is potentially cancer causing.

The official position of those who make their money out of producing and using this technology is that we all know that the only thing that electro magnetic radiation can do is heat and if it doesn’t heat it can’t have any effect.

However, a different view comes from science from reading the people who have researched what happens to cells in laboratories in repeatable experiments. For example, a laboratory took human breast cancer cells, and exposed them to an infusion of melatonin, which is a natural neurohormone which we all have, which helps us sleep at night. Then they applied a very low level of varying electric field, 50 cycles field, and the oncostatic effect of melatonin was totally eliminated.

Every night when we go to sleep our melatonin levels rise and melatonin goes through our blood and cleans our cells up. For example, it scavenges out free radicals which are highly damaging chemicals. If the free radicals persist for very long they damage DNA and cause damaged cells and are shown to be carcinogenic. Melatonin is one of those agents that cleans us up every night to reduce the possibility that cells will become carcinogenic.

That experiment shows that electromagnetic radiation from power lines and appliances can reduce the melatonin cleaning-up effect on human breast cancer cells. The experiment was repeated in three other laboratories. It gave a very reliable and repeatable result. The strength of the signal they used was two to twelve mill gauss – a very low level magnetic field magnitude in that wave.

The European standard for safety for ELF fields is “20,000 mill gauss is safe, whereas this experiment shows that 2 mill gauss causes a significant reduction in the cleansing effect of melatonin on cancer cells.

Common symptoms and signs of melatonin deficiency:

insomnia
difficulty getting to sleep
difficulty falling back to sleep when awaken during the night
light sleeper/easy waking during the night
early morning awakening
un-refreshing sleep
lack of dreaming
family history of insomnia
personal or family history of breast cancer
personal or family history of prostate cancer
prostate enlargement
fatigue
depression
irregular menstrual cycle
unusual menstrual flow (light or heavy)
PMS
scoliosis
poor sleeping prior to menses
anxiety
sensitivity to stress
cataracts
neurodegerative disorder (MS, Parkinson’s, Alzheimer’s, ALS, etc)
elevated cholesterol
high blood pressure
blood clots
heart attack
heart arrhythmias

I do some more reading and it’s available as a suppliment. I read some more about the symptoms of melatonin deficiency and I have a few of the symptoms I decide to get some. Couldn’t hurt to give it a try.

I’ve taken 900 mg of niacin for two days and I’m still vibrating when I wake up. I really thought that it would make a difference. Maybe I need to do it longer. Who knows…

Today I’ll go back to 400 mg of niacin a day and try the melatonin before I go to bed.

June 13, 2006 Posted by | Health | , , , , | Leave a comment

   

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