Diary of Unknown Symptoms

Mystery of the Internal Vibration

Entry for July 16, 2007

After all that I’ve read, I’ll be adding Lecithin tomorrow. I’m not sure where I put the phosphatidylserine…

Here’s some more information I found about the functions of Phosphatidylserine:

Phosphatidylserine (PS)
A natural compound found in all cells, PS is most highly concentrated in the membranes of brain cells which make up about 70% of its nerve tissue mass. (Life Extension, 2002)

Left to its own devices, the brain will succumb to the insults of age, beginning with the fourth or fifth decade of life. Full mental capacity begins its decline as the production of PS slows to suboptimal levels. The net result of an aging brain is cognitive decline, including the gradual loss of the ability to learn, reason, concentrate and remember.

This vital compound plays so many roles that a shortage often creates a variety of symptoms:

  • Phosphatidylserine aids the storage, release and activity of many vital neurotransmitters and their receptors.
  • Phosphatidylserine aids in cell to cell communication.
  • Phosphatidylserine is involved in the maintenance and restoration of nerve cell membranes.
  • Phosphatidylserine stimulates the release of dopamine, a mood regulator that also controls physical sensation and movement.
  • Phosphatidylserine increases the production of acetylcholine, necessary for learning and memory.
  • Phosphatidylserine enhances brain glucose metabolism.
  • Phosphatidylserine reduces cortisol levels (a stress hormone).
  • Phosphatidylserine boosts the activity of nerve growth factor (NGF) which oversees the health of cholinergic neurons.

Phosphatidylserine – Research Summary

Research has shown that dietary supplementation with Phosphatidylserine can slow and even reverse the decline of learning, mood, memory, concentration and word recall related to dementia or age-related cognitive impairment in middle aged and elderly subjects. (Kidd, 1999)

Study #1
In a multi-center Italian study, 87 test subjects aged 55 to 80 were assessed for the effects of Phosphatidylserine on senile mental deterioration. Subjects were given either 300 mg. Phosphatidylserine or a placebo for a period of 90 days. Improvements were noted in the Phosphatidylserine treated group with regards to cognitive functions such as attention, concentration and short term memory. Behavioral measurements also showed improvements in socialization, daily living, self-sufficiency and being more engaged with one’s environment. (Palmieri, 1987)

Study #2
In another study, 51 patients with Alzheimer’s disease were treated for 12 weeks with 300 mg. Phosphatidylserine There were significant improvements in several cognitive functions for the treatment group compared to those given a placebo. Differences were more dramatic among test subjects with less severe cognitive impairment, suggesting that Phosphatidylserine may be useful in the early stages of Alzheimer’s disease. (Crook,1992)


July 15, 2007 - Posted by | Health | ,

No comments yet.

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s

%d bloggers like this: