Diary of Unknown Symptoms

Mystery of the Internal Vibration

Entry for July 16, 2007

After all that I’ve read, I’ll be adding Lecithin tomorrow. I’m not sure where I put the phosphatidylserine…

Here’s some more information I found about the functions of Phosphatidylserine:

Phosphatidylserine (PS)
A natural compound found in all cells, PS is most highly concentrated in the membranes of brain cells which make up about 70% of its nerve tissue mass. (Life Extension, 2002)

Left to its own devices, the brain will succumb to the insults of age, beginning with the fourth or fifth decade of life. Full mental capacity begins its decline as the production of PS slows to suboptimal levels. The net result of an aging brain is cognitive decline, including the gradual loss of the ability to learn, reason, concentrate and remember.

This vital compound plays so many roles that a shortage often creates a variety of symptoms:

  • Phosphatidylserine aids the storage, release and activity of many vital neurotransmitters and their receptors.
  • Phosphatidylserine aids in cell to cell communication.
  • Phosphatidylserine is involved in the maintenance and restoration of nerve cell membranes.
  • Phosphatidylserine stimulates the release of dopamine, a mood regulator that also controls physical sensation and movement.
  • Phosphatidylserine increases the production of acetylcholine, necessary for learning and memory.
  • Phosphatidylserine enhances brain glucose metabolism.
  • Phosphatidylserine reduces cortisol levels (a stress hormone).
  • Phosphatidylserine boosts the activity of nerve growth factor (NGF) which oversees the health of cholinergic neurons.

Phosphatidylserine – Research Summary

Research has shown that dietary supplementation with Phosphatidylserine can slow and even reverse the decline of learning, mood, memory, concentration and word recall related to dementia or age-related cognitive impairment in middle aged and elderly subjects. (Kidd, 1999)

Study #1
In a multi-center Italian study, 87 test subjects aged 55 to 80 were assessed for the effects of Phosphatidylserine on senile mental deterioration. Subjects were given either 300 mg. Phosphatidylserine or a placebo for a period of 90 days. Improvements were noted in the Phosphatidylserine treated group with regards to cognitive functions such as attention, concentration and short term memory. Behavioral measurements also showed improvements in socialization, daily living, self-sufficiency and being more engaged with one’s environment. (Palmieri, 1987)

Study #2
In another study, 51 patients with Alzheimer’s disease were treated for 12 weeks with 300 mg. Phosphatidylserine There were significant improvements in several cognitive functions for the treatment group compared to those given a placebo. Differences were more dramatic among test subjects with less severe cognitive impairment, suggesting that Phosphatidylserine may be useful in the early stages of Alzheimer’s disease. (Crook,1992)

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July 15, 2007 Posted by | Health | , | Leave a comment

Entry for July 15, 2007

Discovered this today about choline and phosphatidylserine. When I went into a health food store back in January looking for Phosphorus I was given something called Phosphatidylserine or “Ps-100” for short. I was miffed at the time because it wasn’t phosphorus so I googled and read about how it used for the brain and I wasn’t really interested. Now I discover that phosphatidylserine is very linked to choline and Lecithin so this time round…I’m very interested!

So although it wasn’t phosphorus, it was a very important link to choline which of course is linked to phosphorus.

How Do You Improve Your Memory?

Wouldn’t it be nice if our brain was like a computer? Just load the programs in and all the information would be there whenever it was needed. The fact is that our brain is a computer much better than any you can buy in stores.

Dr. Wilder Penfield, a well known Canadian neurosurgeon, discovered that all of our memories are recorded by the brain; our problem is that we don’t practise retrieving this information and the memories are lost. We have to work on memory retrieval because it takes no effort to forget things. Another difference is that the brain is a living computer which requires optimal nutrition if we want it to work its best. One of the first computer phrases I remember learning was “garbage in, garbage out.” This means that if you program your computer with garbage programs, then you should expect the information coming out to be garbage. Well, the same applies to your brain; if you feed it garbage, then you can expect the memory information to be garbage.

The brain also needs physical exercise and mental exercise if we wish to increase the power of memory. Many research studies have shown that mental activity keeps the brain healthy and increases the strength of your memory. These activities include learning new things, keeping active in social interaction, and doing puzzles or other games which stimulate thought.

As we age, it is normal to have changes in memory but, just as with every other organ of the body, the brain can have its capacity to function rapidly diminished through poor nutrition. We do have the option of adopting good health habits as outlined in this article and actually improving brain function and memory.

Two major physiological changes seen in the brain with age and associated memory loss are the following: first, there is a decrease in the ability of the nerves to exchange information between each other because of a decrease in neural synapse. A neural synapse is like a tiny spark which occurs between nerves when information is transferred. If the nutritional material is not present, then the spark will not occur or will be diminished. The second sign of an aging brain is a decrease in blood going to the brain and circulating through it, which is an action known as cerebrovascular disease.

The brain requires a large amount of energy to work properly as well as a good circulatory system to provide glucose, oxygen and nutrients. The brain also has a protective membrane called the blood-brain barrier which is designed to deny access to substances which may be harmful to the brain. If this blood-brain barrier and the arteries which supply the brain are blocked by a buildup of cholesterol and triglycerides, then the brain suffers. A good example of how sensitive the brain is to nutritional changes can be seen by looking at the symptoms of hypoglycemia, which is defined as a decreased amount of glucose available to the brain. The symptoms are as follows: fatigue, light headedness, headache, irritability, depression, anxiety, confusion, mental disturbance, and insomnia.

Ginkgo Biloba
One of the most studied herbal remedies, Ginkgo Biloba has been through 40 double-blind studies on its effectiveness. Ginkgo Biloba is a registered drug in Germany and France for the treatment of cerebrovascular disease which causes the restriction of blood flow which in turn leads to cerebral deterioration and memory loss. These medical studies showed that Ginkgo Biloba was specifically indicated for increasing cerebrovascular circulation and that it caused a reversal in brain deterioration. Studies show that increased vascular flow occurred within 6 to 8 weeks and that improvement continued for up to 24 weeks. With increased vascular flow, previous problems of short term memory loss, lack of concentration and headaches improved.

Lecithin
Lecithin is the best known of the phosphatides and is essential for normal brain function. Lecithin also contains choline which is used by the body to produce the neurotransmitter acetylcholine – one of the chemicals which allow for the neural synapse to communicate information. Failure to produce these chemicals results in poor memory. Another function of choline is to increase the strength of the neural cell membrane and thus the health of the brain and nerve cells. Lecithin is also known as a lipotropic factor; this means that it is used for the transport of fatty material through the blood stream and liver. Without lipotropic factors, the blood vessels and liver become clogged with fat which prevents the formation of choline while decreasing circulation to the brain.

Phosphatidyl Serine
This substance is another very important nutrient for maintaining healthy brain cells because it also helps to produce choline. Decreased blood serum levels of Phosphatidyl Serine in elderly patients have been linked to impaired memory function and depression. The body can produce choline from Phosphatidyl Serine which is then transformed by the body into acetylcholine which is a very important neurotransmitter and improves communication between the nerves. Very good results have been shown in scientific research when Phosphatidyl Serine was used to treat depression, impaired memory and your mood. As previously discussed, Phosphatidyl Serine is also responsible for maintaining healthy brain and nerve cells, and the chemicals that maintain neural synapse. Antioxidants are also essential for helping the body protect itself from free radical damage which will lead to neural degeneration.

Closing Thoughts
Adopting the above recommendations to improve the brain and thus memory is an important step, but there are certain things that you should avoid. The first is heavy use of alcohol because brain deterioration is well documented in alcoholics. Secondly, avoid contact with aluminum and lead such as can be found in, respectively, aluminum cookware and paint. Lead has a long history of causing neural deterioration. Although the cause of Alzheimer’s Disease is not yet known, a common link in Alzheimer patients is a high level of aluminum found in the brain. Thirdly, low blood sugar levels such as those found in hypoglycemia cause starvation of the brain because it requires large amounts of energy from glucose in order to work. This starvation of the brain will lead to poor memory. The use of barbiturates and psychotropic drugs will also cause brain deterioration. People who suffer from either Diabetes Mellitus or Hypothyroidism should also take steps to prevent deterioration of memory through proper nutrition.

By Dr. Daryl Robert Bourke, DC ND

July 15, 2007 Posted by | Health | , , | Leave a comment

Entry for July 15, 2007

Day one: The treatment with phosphorus was a success. The cold hands that I’ve had all week didn’t happen once today. Didn’t get the weird nerve feelings in my head either.

With the added research from this weekend, I’ve discovered that phosphorus plays a role in the creation of lecithin and I found my bottle half full from the last time I tried it. Lecithin contains a B vitamin called Choline. Here’s what I found:

Choline

Although choline is not by strict definition a vitamin, it is an essential nutrient. Despite the fact that humans can synthesize it in small amounts, choline must be consumed in the diet to maintain health. The majority of the body’s choline is found in specialized fat molecules known as phospholipids, the most common of which is called phosphatidylcholine or lecithin.

Support of Nervous System Activity

Choline is a key component of acetylcholine, a messenger molecule found in the nervous system. Acetylcholine, also called a neurotrasmitter since it carries messages from and to nerves, is the body’s primary chemical means of sending messages between nerves and muscles. Because of its role in nerve-muscle function, choline (supplemented in the form of lecithin, or phosphatidylcholine), has been used experimentally to help improve neuromuscular function in Alzheimer’s disease.

July 15, 2007 Posted by | Health | , , , | Leave a comment

Entry for July 15, 2007

And yet another amazing clue regarding phosphorus… a zinc deficiency is associated with a low level of phosphorus!!

Functions Of Phosphorus

Zinc is required for protein synthesis. Often a low phosphorus level is associated with a zinc deficiency, cadmium toxicity, or zinc loss. When these imbalances are corrected, the phosphorus level improves.

Digestive – regulates absorption of calcium and a variety of trace elements. Phosphorus in excess has a laxative action
Nervous – source of adenosine triphosphate (ATP), component of the myelin sheath
Endocrine – interacts with vitamin D
Blood – red blood cell (RBC) metabolism
Muscular – adenosine triphosphate (ATP) needed for muscle contraction
Skeletal – component of bone and teeth
Immune – adenosine triphosphate (ATP) for leukocytes
Metabolic – energy production via phosphorylation reactions
Detoxification – in liver – via adenosine triphosphate (ATP)

Sources Of Phosphorus

Seafood – tuna, mackerel, pike, red snapper, salmon, sardines, whitefish, scallops, shad, smelt, anchovies, bass, bluefish, carp, caviar, eel, halibut, herring, trout

Meats – liver (beef, chicken, hog, lamb), rabbit, sweetbreads, turkey, beef brains, chicken, eggs, egg yolk, lamb heart, kidney

Nuts/seeds – pinon, pistachios, pumpkin, sesame, sunflower, walnuts, almonds, brazil nuts, cashews, filberts, hickory, peanuts, pecans

Vegetables – chickpeas, garlic, lentils, popcorn, soybeans

Dairy – cheeses

Grains – wheat bran and germ, wild rice, buckwheat, millet, oats, oatmeal, brown rice, rice bran, rye, wheat

Miscellaneous – chocolate, kelp, yeast, bone meal

July 15, 2007 Posted by | Health | , | Leave a comment

Entry for July 15, 2007

Here’s an excerpt from Dr. Jenson’s guide to Body Chemistry and Nutrition. I read this book several months ago and it was great. But now I was looking for something on phosphorus and what a gold mine. This guy is incredible!

“sugar upsets the calcium-phosphorus balance.”

Phosphorus

Phosphorus does not occur in a free state but in the form of phosphates and alkaline salts. It is in the bones in the form of calcium and magnesium phosphate (where it does not glow in the dark) and is an important electrolyte as well. Blood concentrations of phosphorus and calcium reveal a teeter-totter effect-if one is up the other is down. The body contains about 800 grams of phosphorus at any particular time. It Buctuates in its interaction with calcium and requires the help of vitanlin D to be assimilated &-om the small intestine. Seventy to 80 percent of this stored phosphorus is in the bones and teeth, 10 percent is in muscle tissue, and the rest is in the blood, the cells, the fluid surrounding the cells, and in the nerves and brain. Phosphorus, like calcium, is needed by every cell in the body.

Phosphorus plays the starring role in many body functions. As a key ingredient of the energy production process in every cell of the body, adenosine triphosphate helps transform glucose into energy and carbon dioxide. Most enzyme reactions involving B-complex vitamins as cofactors can only take place in the presence of phosphorus. As an essential part of the nucleic acids DNA and RNA, it influences cell reproduction and protein formation.

Phosphorus helps transport and break down fats. A chemical called phosphocreatin energizes muscle contractions. Lecithin, which contains phosphorus, helps keep cholesterol in solution so it can’t deposit on arterial walls and cause cardiovascular disease. Male seminal fluid is mostly lecithin. Lecithin helps substances pass through cell membranes and participates in breaking down fats. About 70 percent of the phosphorus in foods is assimilated into our bodies, unlike calcium, of which only 20 to 30 percent is absorbed from food in the small intestine.

Excess phosphorus and magnesium in the blood hinder absorption of calcium from food. (Calcium, in turn, hinders absorption of iron.) If the intake of calcium, phosphorus, or vitamin D is too low, bones don’t grow properly. Phosphorus, in the form of electrically charged phosphate ions, has a significant influence on water balance and osnlotic pressure in the body. Phosphate in the blood helps maintain the acid-alkaline balance. An acid phosphate (monosodium phosphate) works with an alkaline phosphate (disodium phosphate) to stabilize this balance.

Healing of broken bones, rickets, and osteomalacia is speeded up when there is sufficient phosphorus working with calcium and vitamin D.

CAUSES OF PHOSPHORUS DEFICIENCY

Antacids with aluminum block phosphorus intake, as will an excess of iron. Lack of vitamin D or a high blood level of calcium will block phosphorus assimilation. The hormone calcitonin causes rapid loss of phosphorus, and sugar upsets the calcium-phosphorus balance.

From another web site, I found this:

Fructose: A recent study of 11 adult men found that a diet high in fructose (20% of total calories) resulted in increased urinary loss of phosphorus and a negative phosphorus balance (i.e., daily loss of phosphorus was higher than daily intake). This effect was more pronounced if the diet was also low in magnesium.

A potential mechanism for this effect is the lack of feed back inhibition of the conversion of fructose to fructose-1-phosphate in the liver. In other words, increased accumulation of fructose-1-phosphate in the cell does not inhibit the enzyme that phosphorylates fructose, using up large amounts of phosphate. This phenomenon is known as phosphate trapping.

This finding is relevant because fructose consumption in the U.S. has been increasing rapidly since the introduction of high fructose corn syrup in 1970, while magnesium intake has decreased over the past century.

July 15, 2007 Posted by | Health | , | Leave a comment

Entry for July 15, 2007

Success! Woke up with no vibration.

Found more interesting facts about phosphorus:

There is a distinct difference between the phosphorus needed by the bones from the phosphorus needed by the brain. Phosphorus for the brain comes from meat, dairy and fish whereas phosphorus for the bones comes from fruits and vegetables.

Phosphorus is vital in synthesizing lecithin and cerebrin, which are both needed by the brain. Phosphorus compounds like lecithin are found everywhere in the tissues, lymph, and other of the body as well as in the white and gray matter of brain and nerve tissue.

Phosphorus stimulates hair growth and prevents the blood from becoming too acid or alkaline. It is also necessary for the synthesis of the RNA and DNA.

So there are different types of phosphorus and the type I’m interested in is for the brain. So I need to change my diet to include more meat, dairy and fish. But it doesn’t mention anything about the breakfast cereals…

Yesterday we did our shopping and I checked almost all of the cereals for the phosphorus content and All Bran was the winner. It has 35% phosphorus and 50% magnesium in half a cup. WOW! that’s a lot of both so I’ll have a small bowl for breakfast and organize my new vitamin schedule.

Daily Supplements

1.5 of calcium complex which contains 150 mg of magnesium
125 mg extra magnesium
50 mg zinc
75 mg maganese (25 mg 3 times a day)
375 mcr molybdendum

July 15, 2007 Posted by | Health | , , , , , , , , | Leave a comment

   

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