Diary of Unknown Symptoms

Mystery of the Internal Vibration

Entry for August 26, 2006

So what is the Q10 exactly? I do a bit of research:

How it Functions

Energy Production

Coenzyme Q lies at the heart of our cells’ energy producing process. Special organelles (tiny organs) inside our cells, called mitochondria, take fat and other substances and convert them into usable energy. This process always requires coenzyme Q. In some cells, like heart cells, this energy conversion process can be the difference between life and death – and so can the activity of coenzyme Q.

Cell Protection

Coenzyme Q is a well-established antioxidant used by the body to protect cells from oxygen damage. The exact mechanism for this protective effect is not clear. Nevertheless, up to 95% less damage to cell membranes has been demonstrated following supplementation with coenzyme Q.

The antioxidant protection that can be supplied by coenzyme Q has prompted clinicians to use this nutrient in a wide variety of heart-related conditions in which the heart muscle needs special protection from oxygen damage. These conditions include arrhythmia, angina, heart attack, mitral valve prolapse, high blood pressure, coronary artery disease, atherosclerosis, and congestive heart failure.

And I also found this:

Boosts energy and brain power

Coenzyme Q10 is a great boost to heart health, but it has many other beneficial effects. Strenuous physical exercise reduces blood levels of CoQ10 and supplementation with 60 mg/day has been found to improve athletic performance. Administration of CoQ10 alone or in combination with vitamin B6 (pyridoxine) boosts the immune system and may be useful in the treatment of AIDS and other infectious diseases. An adequate level of CoQ10 in the body is essential to proper muscle functioning and several studies have indeed shown that supplementation with 100-150 mg/day of CoQ10 markedly improves the condition of people suffering from muscular dystrophy.

Many overweight people have very low levels of CoQ10 and supplementation may enable them to lose weight due to the effect of CoQ10 in speeding up the metabolism of fats.

Some very recent, highly intriguing research carried out at the Institute of Neurosciences in Argentina has shown that brain activity and alertness is enhanced in hypertensive patients within one hour of oral administration of 100 mg of CoQ10.

Keeps your gums healthy and fights cancer

CoQ10 has been used with success in combating periodontal diseases, especially gingivitis (gum disease). Tissue affected by gingivitis is deficient in CoQ10 and experiments have shown that supplementation with as little as 50 mg/day can decrease inflammation. More recent research has shown that topical application of CoQ10 dissolved in soy oil (85 mg/ml) to affected areas (periodontal pockets) reduces bleeding and the depth of the pockets.

Research carried out in Denmark has provided some tantalizing evidence that CoQ10 may also be effective in the fight against certain cancers. A trial involving the treatment of 32 breast cancer patients with mega doses of vitamins, minerals, essential fatty acids and coenzyme Q10 (90 mg/day) in addition to conventional therapy showed a highly beneficial effect of the supplementation. Two of the patients in the trial whose tumours had not regressed had their CoQ10 dosages increased to 390 mg/day and 300 mg/day respectively with the result that their tumours disappeared completely within three months. CoQ10 supplementation is also very important for cancer patients undergoing chemotherapy with heart toxic drugs such as adriamycin and athralines. Recent research has also shown that certain cholesterol-lowering drugs (lovastatin, etc.) block the natural synthesis of CoQ10 so supplementation with 100 mg/day is recommended for patients taking these drugs.

So how much do you need?
The body can synthesize coenzyme Q10 and it is also found in several dietary sources, notably organ meats. The level of CoQ10 in human organs peaks around the age of 20 years and then declines fairly rapidly. The decrease in CoQ10 concentration in the heart is particularly significant with a 77-year-old person having 57 per cent less CoQ10 in the heart muscle than a 20-year- old. Some experts involved in CoQ10 research believe that many people, especially older people and people engaging in vigorous exercise may be deficient in CoQ10 and may benefit from supplementation. The recommended daily dosage for health maintenance is 30 mg; however, considerably higher amounts are required in the treatment of the various diseases for which supplementation has been found beneficial. CoQ10 should be taken with a meal containing some fat or even better, in combination with soy or vegetable oil which enhances its absorption quite substantially. The body readily absorbs CoQ10 supplements and no toxic effects have been reported for daily dosages as high as 300 mg. The safety of CoQ10, however, has not been established in pregnancy and lactation, so caution is advised here until more data becomes available.


August 26, 2006 - Posted by | Health |

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