Diary of Unknown Symptoms

Mystery of the Internal Vibration

Entry for July 27, 2006

Today I noticed that my tongue was slighty sore and itchy. I check it in the mirror and I have a white mucus on top. I show it to my wife and she thinks it’s thrush. So I stop taking the Brewer’s Yeast and increase the acidophilus.

Found some more information on Riboflavin Deficiency: 

Vitamin B2 (riboflavin) is a component of several enzymes necessary for carbohydrate, fat and protein metabolism.

Riboflavin is important for flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN). These compounds help regulate cellular metabolism through oxidation-reduction reactions.

Sources: Riboflavin is the yellow-green pigment of skim milk and whey. Other sources are meats, nonfat milk and oysters. The vitamin is very sensitive to destruction by light. To protect the vitamin, milk is better distributed to the consumer in packages rather than clear bottles.

Health Issues: A deficiency of riboflavin can result in decreased growth, nervous disorders, degeneration of nerve myelin sheaths, edema and photophobia.

Pharmacokinetics: Vitamin B2 is readily absorbed from the upper gastrointestinal tract, except in the presence of malabsorption syndromes. The extent of gastrointestinal absorption is increased when the drug is administered with food and is decreased in patients with hepatitis, cirrhosis, biliary obstruction.

Vitamin B2 is inactive until phosphorylated to flavin mononucleotide (FMN) in gastrointestinal mucosal cells, erythrocytes and the liver; FMN is converted to another coenzyme, flavin adenine dinucleotide (FAD). Free vitamin B2 is present in the retina. In blood, about 60% of FAD and FMN is protein bound.

The biologic half-life is about 66 to 84 minutes following oral or i.m. administration of a single large dose in healthy individuals.

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July 27, 2006 Posted by | Health | , , , | Leave a comment

Entry for July 27, 2006

Some google searching and I’ve found four supplements with 6mg of Riboflavin Butyrate in the ingredients. The only problem? They are from North Korea, Toyko and Japan.

1) Vitaalto C Tablet 2000
2) SAMON Chondro-vital
3) HEALTHDIN SOFT CAP
4) Maxcon Vitagreen Soft Capsule (Sodium Chondroitin Sulfate)

I’ve got to find out if these products are available in Canada.

July 27, 2006 Posted by | Health | | Leave a comment

Entry for July 27, 2006

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It’s now getting late in the day and I call into work to tell them I won’t be back in the office. I explain to my co-worker about the events from the afternoon and I’m about to embark downtown to Sick Kids to find out if they have B2 for injections.

She does a quick google search and apparently new born babies are sometimes injected with B2 if there is a deficiency. This is great news so she agrees to look up the pharmacy at Sick Kids and call them for me.

After a brief pause, she comes back on the phone and says they don’t have it. The person she spoke to explained that Sick Kids actually uses Shoppers Drug Mart at the bottom of their building. There is a internal pharmacy but that is only used for the kids and not available to the public.

I can’t get a break anywhere. She suggests that I call Health Canada to find out if B2 injections are available in Canada. That’s a great idea so I call them and leave a message on a machine with my cell number.

I go back to the doctor’s office and I tell him what the pharmacy said and about Sick Kids. He suggests that I keep taking my B1 and B2 suppliments at the recommended dosage until I get to the neurologist.

Not the answer I was looking for but I guess I have no choice. In the meantime I can keep looking. I contact Telehealth just to see what the response would be and they couldn’t really help me and I didn’t expect them too. She suggested contacting Health Canada and I’ve already done that.

Here we go again… and still vibrating…

July 27, 2006 Posted by | Health | , , | Leave a comment

Entry for July 27, 2006

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At the pharmacy downstairs, I hand them my prescription and I’m half expecting them to say they don’t have it. She asks me for my health insurance card and she types it into their system.

WOW! Looks like this time I’ll have success!

She hands me the medication and I can’t believe it. I have it in my hands! I take a closer look at the package and it says “CYANOCOBALAMIN”. Huh? Isn’t that B12?

I go back to the pharmacist and I ask her if I have B2 or B12? She confirms that it is B12 and I explain that I needed B2. She takes it back and checks the computer. They don’t have any but she’s willing to make a few phone calls.

After her calls, she explains that B2 is not available for injection. Only B12. She suggests trying the Hospital for Sick Kids as they will have a bigger list of distributors.

July 27, 2006 Posted by | Health | , | Leave a comment

Entry for July 27, 2006

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My day has arrived. Follow up with the doctor today for the B2 injection. He writes me a prescription and tells me to go to the pharmacy downstairs. He said they might not have it so I may have to try a couple of them. Then once I have it, I’ll bring it back and he’ll give me the needle.

At least now I have the prescription.

July 27, 2006 Posted by | Health | , , , | Leave a comment

Entry for July 25, 2006

Then I find this:

Absorption of Riboflavin

People with stressful lives should take a daily B complex vitamin supplement with about 25mg of riboflavin.

Vitamin B2 called Riboflavin belongs to a group of yellow fluorescent pigments called flavins and is responsible for the bright yellow color of the urine when excreted. Because it is water soluble like all the B vitamins, it is not easily stored in the body and needs to be present in adequate amounts in the diet or taken in supplement form on a daily basis. Absorbed through the first segments of the small intestines, it is better if supplements of the second B vitamin are taken with food. The absorption rate is increased four fold from approximately 15% without food to 60% with food.

Riboflavin absorption rate is increased 60% with food. No one ever told me this. Could this be why I’ve been taking it for so long without results?

July 27, 2006 Posted by | Health | , , | Leave a comment

Entry for July 25, 2006

Trouble in paradise… A do a bit of research tonight and find this article:

Riboflavin:The Dose Makes the Poison

Naturally occurring riboflavin found in our skin and eyes has been implicated to play a pivotal role in many of the damaging effects of UV light exposure. This includes damage to our skin’s connective tissue, the induction of DNA lesions known to promote the development of skin cancer and aging, and the impairment of mitochondria functioning resulting in cell death. High doses of riboflavin have also been shown to induce damage to retina cells in the eyes of research animals.

Surprisingly, while the combination of riboflavin and light has been studied because of its adverse effects on cells grown in culture and exposed to light—and riboflavin and light have been used as a model for inducing things as diverse as liver dysfunction, cataracts and mutations—the nutrition industry has failed to heed the warning that damage may be caused by high doses of riboflavin supplements.

This is partly due to confusion because a diet deficient in riboflavin is a risk factor for things like cataracts, while at the same time, the combination of riboflavin and light is often used by scientists to cause cataracts in animal research. As always, the dose makes the poison, and this means that if you take nutritional supplements you should make sure you consume an adequate amount of riboflavin daily, rather than an excess of riboflavin.

The human requirement for riboflavin is less than 2 milligrams a day, but many common vitamin supplements contain 10s or 100s of milligrams. There is little (if any) scientific justification for taking supplements of riboflavin greatly in excess of the known dietary requirement. However, there is a lot of scientific evidence and speculation that the combination of abnormally high blood, eye and skin levels of riboflavin, combined with a lifetime of sun exposure, may have serious negative consequences, and actually cause the damage we are trying to prevent. The combination of sunlight and abnormally high tissue levels of riboflavin from excess supplementation is a toxic combination that should be avoided.

July 27, 2006 Posted by | Health | , | Leave a comment

Entry for July 25, 2006

Today I have a job interview so I’d thought I would very careful about the vitamins. I’ll go back to what made me feel the best. Vitamin C and Acidophilus.

About an hour before the interview, I notice that my hands and feet are cold so I take a magnesium pill (150 mg). My cold hands disappear within twenty minutes and I go to the interview.

By the end of the day, I don’t take anymore vitamins and I’m feeling really good.

July 27, 2006 Posted by | Health | , , , | Leave a comment

   

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