Diary of Unknown Symptoms

Mystery of the Internal Vibration

Entry for July 11, 2006

1152668691-hr-443

Went to the Chiropractor today. Another appointment of stretching and the Thumper. As he’s working he says I have a few knots in my upper shoulder, my lower back is still stiff but my neck has improved.

He hooks me up to a machine, places four sensors on my back and it starts vibrating. He says it will turn off automatically and that’s the end of my appoinment.

For ten minutes it goes through a cycle of different massages.

Advertisements

July 11, 2006 Posted by | Health | | Leave a comment

Entry for July 11, 2006

Out of curiosity, I email the lab to find out how long it takes for a Thiamine test. I wanted to see if I got the same answer. Here is the response:

Thiamine is done at a GDML location. Turn Around Time is approx 15 working days. Specimen must be separated and frozen 30 minutes after collection.  Please call the Billing Dept for the cost.

So I’m guessing that 15 working days takes me until July 7th (Last Friday) Today is Tuesday so it should be anyday now.

July 11, 2006 Posted by | Health | , | Leave a comment

Entry for July 11, 2006

Now that I’ve established that the lab has completed the test results, I give the doctor’s office until noon to call me. There is no call so I contact them. I speak to the secretary and she searches the computer and says they are still waiting for the test results. I explain that I contacted the lab and they told me it was completed. She checks again and puts the phone down. She comes back after a few minutes and explains that they do not have the results. So it’s back to the lab. They have the B12 result but are still waiting for Folate, CRP and Thiamine. She says that if there is anything abnormal about the results, the lab will call them directly.

I call the lab again and explain that I’m looking for my test results. She looks it up in the computer and tells me they have been completed. I explain that I just got off the phone from the doctor’s office and they have not yet received the results. She asks me to name the type of tests that are still outstanding: Folate, CRP and Thiamine. She explains that the results have been sent twice to my doctor and that the Thiamine test takes 15 days and it’s not completed yet. The doctor’s office only has one of the test results so I ask her to fax the results again.

What a joke. No patient should have to go through this.

July 11, 2006 Posted by | Health | , | Leave a comment

Entry for July 11, 2006

MAGNESIUM MAINTAINS NORMAL NERVE, BRAIN, & MUSCLE FUNCTION

While 60% of the Mg is in the bones, the rest is primarily in the cells where it functions to regulate the transmission of impulses between brain cells, & from nerves to muscles & organs. It also maintains normal muscle function & contractility.

Since Mg regulates the irritability or sensitivity of the nerves & muscles, a deficiency leads to neuromuscular hyperexcitability which can be associated with muscle cramps, twitches, & tremors, tension, tightness, or soreness. It is also associated with various spasms, such as the bronchospasm of asthma, esophageal spasm ( a lump in the throat with difficulty swallowing), the vascular spasm of migraines some forms of hypertension, chest pain & other chronic pain syndromes, the urinary spasms with some forms of urinary problems & bedwetting, the spasms of premature labor & menstrual cramps, & of course the spasms of seizures.

The excitability can also be associated with an easy startle response, noise & light sensitivity, numbness & tingling & strange body sensations.

Some of the most dramatic effects of Mg deficiency may occur in the central nervous system such as with the DT’s (delirium tremens) of alcoholism, general anxiety & irritability, nervousness, confusion, tantrums, insomnia,and depression.

July 11, 2006 Posted by | Health | , , , | Leave a comment

Entry for July 11, 2006

New clues about vitamin D function in the nervous system

Accumulating data have provided evidence that 1 alpha,25 dihydroxyvitamin D(3) [1,25-(OH)(2)D(3)] is involved in brain function. Thus, the nuclear receptor for 1,25-(OH)(2)D(3) has been localized in neurons and glial cells. Genes encoding the enzymes involved in the metabolism of this hormone are also expressed in brain cells.

The reported biological effects of 1,25-(OH)(2)D(3) in the nervous system include the biosynthesis of neurotrophic factors and at least one enzyme involved in neurotransmitter synthesis. 1,25-(OH)(2)D(3) can also inhibit the synthesis of inducible nitric oxide synthase and increase glutathione levels, suggesting a role for the hormone in brain detoxification pathways.

Neuroprotective and immunomodulatory effects of this hormone have been described in several experimental models, indicating the potential value of 1,25-(OH)(2)D(3) pharmacological analogs in neurodegenerative and neuroimmune diseases. In addition, 1,25-(OH)(2)D(3) induces glioma cell death, making the hormone of potential interest in the management of brain tumors.

These results reveal previously unsuspected roles for 1,25-(OH)(2)D(3) in brain function and suggest possible areas of future research.

July 11, 2006 Posted by | Health | , | Leave a comment

Entry for July 11, 2006

For three days in row now I’ve had no vibration at night but I have it when I wake up. I am now starting to suspect that it’s linked to a Vitamin D deficiency.

So here we go again…

Vitamin D Deficiency

In vitamin D deficiency, calcium absorption cannot be increased enough to satisfy the bodys calcium needs. Consequently, PTH production by the parathyroid glands is increased and calcium is mobilized from the skeleton to maintain normal serum calcium levels a condition known as secondary hyperparathyroidism. Although it has long been known that severe vitamin D deficiency has serious consequences for bone health, recent research suggests that less obvious states of vitamin D deficiency are common and increase the risk of osteoporosis and other health problems.

Importance

Very important in infancy and childhood; healthy bone formation; healthy nervous system maintenance; good for thyroid gland, skin, teeth, normal blood clotting.

Enhances Absorption

Phosphorus, calcium, choline and vitamins A, C, F.

Vitamin D is vital to the human body as it promotes absorption of calcium and magnesium, which are essential for the normal development of healthy teeth and bones. It also helps maintain adequate levels of calcium and phosphorus in the blood.

Muscle Weakness and Pain

Vitamin D deficiency causes muscle weakness and pain in children and adults. Muscle pain and weakness was a prominent symptom of vitamin D deficiency in a study of Arab and Danish Moslem women living in Denmark. In a cross-sectional study of 150 consecutive patients referred to a clinic in Minnesota for the evaluation of persistent, nonspecific musculoskeletal pain, 93% had serum 25(OH)D levels indicative of vitamin D deficiency. A randomized controlled trial found that supplementation of elderly women with 800 IU/day of vitamin D and 1,200 mg/day of calcium for three months increased muscle strength and decreased the risk of falling by almost 50% compared to supplementation with calcium alone.

Hypertension (High Blood Pressure)

The results of epidemiological and clinical studies suggest an inverse relationship between serum 1,25(OH)2D levels and blood pressure, which may be explained by recent findings that 1,25(OH)2D decreases the expression of the gene encoding renin (see Function). Data from epidemiological studies suggest that conditions that decrease vitamin D synthesis in the skin, such as having dark skin and living in temperate latitudes, are associated with increased prevalence of hypertension. A controlled clinical trial in 18 hypertensive men and women living in the Netherlands found that exposure to UVB radiation three times weekly for six weeks during the winter increased serum 25(OH)D levels and significantly decreased 24-hour ambulatory systolic and diastolic blood pressure measurements by an average of 6 mm Hg. In randomized controlled trials of vitamin D supplementation, a combination of 1,600 IU/day of vitamin D and 800 mg/day of calcium for eight weeks significantly decreased systolic blood pressure in elderly women by 9% compared to calcium alone, but supplementation with 400 IU/day or a single dose of 100,000 IU of vitamin D did not significantly lower blood pressure in elderly men and women over the next two months. At present, data from controlled clinical trials are too limited to determine whether vitamin D supplementation will be effective in lowering blood pressure or preventing hypertension.

Tolerable Upper Intake Level

Adults 19 years and older 50 mcg (2000 IU)

So vitamin D is used in the aborption of calcium and magnesium. Could this be why there has been no improvement despite taking a calcium/magnesium suppliment? Interestingly with the success I’ve had in the past three days, I’ve managed to increase my calcium, magnesium and added vitamin D to my daily intake. Coincidence?

Calcium Balance

Maintenance of serum calcium levels within a narrow range is vital for normal functioning of the nervous system, as well as for bone growth, and maintenance of bone density. Vitamin D is essential for the efficient utilization of calcium by the body. The parathyroid glands sense serum calcium levels, and secrete parathyroid hormone (PTH) if calcium levels drop too low. Elevations in PTH increase the activity of 25(OH)D3-1-hydroxylase enzyme in the kidney, resulting in increased production of 1,25(OH)2D. Increasing 1,25(OH)2D production results in changes in gene expression that normalize serum calcium by

1) Increasing the intestinal absorption of dietary calcium.

2) Increasing the reabsorption of calcium filtered by the kidneys.

3) Mobilizing calcium from bone when there is insufficient dietary calcium to maintain normal serum calcium levels. Parathyroid hormone and 1,25(OH)2D are required for the latter two effects.

And with that. I’ll increase my vitamin D to 2000 IU per day. It will be interesting to see if that makes a difference on the morning vibration.

July 11, 2006 Posted by | Health | , , , | Leave a comment

   

%d bloggers like this: